Chemistry:Isopropylmalic acid

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Isopropylmalic acid
2-Isopropylmalic acid.svg
2-Isopropylmalic acid
3-Isopropylmalic acid.svg
3-Isopropylmalic acid
Names
IUPAC names
3-Isopropylmalic acid
2-Hydroxy-3-isopropylsuccinic acid
Other names
Isopropylmalate
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
DrugBank
EC Number
  • (2): 630-924-5
UNII
Properties
C7H12O5
Molar mass 176.168 g·mol−1
Hazards
GHS pictograms GHS07: Harmful
GHS Signal word Warning
H315, H319, H335
P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362, P403+233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

Isopropylmalic acid (isopropylmalate) is an intermediate in the biosynthesis of leucine, synthesized from oxoisovalerate by 2-isopropylmalate synthase and converted into isopropyl-3-oxosuccinate by 3-isopropylmalate dehydrogenase. Two isomers are important, the 2- and 3-isopropyl derivatives, and these are interconverted by isopropylmalate dehydratase.