Chemistry:LAG525
From HandWiki
LAG525 is a monoclonal antibody being developed by Novartis for the treatment of cancer. The antibody targets the immune checkpoint LAG-3, which is expressed on T cells and tends to down-regulate an immune response. In a June 2015 presentation Novartis management indicated that 'dosing is imminent' for the first clinical trials of LAG525.[1]
LAG525's first clinical trial is a Phase I in expected to be in patients with various solid tumors, in combination with PDR001, an anti-PD-1 monoclonal antibody. (ClinicalTrials.gov identifier NCT02460224).
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