Chemistry:Lividomycin

Lividomycin
Identifiers
	IUPAC name (1R,2R,3S,4R,6S)-4,6-Diamino-3-hydroxy-2-{[α-D-mannopyranosyl-(1->4)-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1->3)-β-D-ribofuranosyl]oxy}cyclohexyl 2-amino-2,3-dideoxy-α-D-ribo-hexopyranoside;
CAS Number	36441-41-5 ;
PubChem CID	72394;
DrugBank	DB04728;
ChemSpider	65327;
UNII	A606AJ494W;
ChEBI	CHEBI:71961 ;
ChEMBL	ChEMBL389029;
Chemical and physical data
Formula	C29H55N5O19
Molar mass	777.775 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O([C@H]4[C@H](O[C@@H]3O[C@H](CO)[C@@H](O[C@H]2O[C@@H](CN)[C@@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O)[C@H](O)[C@H]2N)[C@H]3O)[C@@H](O)[C@H](N)C[C@@H]4N)[C@H]5O[C@@H]([C@@H](O)C[C@H]5N)CO;
	InChI InChI=1S/C29H55N5O18/c30-3-11-23(51-28-20(43)19(42)17(40)13(5-36)47-28)18(41)15(34)27(45-11)50-24-14(6-37)48-29(21(24)44)52-25-16(39)7(31)1-8(32)22(25)49-26-9(33)2-10(38)12(4-35)46-26/h7-29,35-44H,1-6,30-34H2/t7-,8+,9-,10+,11+,12-,13-,14-,15-,16+,17-,18-,19+,20+,21-,22-,23-,24-,25-,26-,27-,28-,29+/m1/s1; Key:DBLVDAUGBTYDFR-SWMBIRFSSA-N;

Short description: Chemical compound

Lividomycin is a broad-spectrum aminoglycoside antibiotic.^[1] It is effective against most gram positive and gram negative bacteria including Mycobacterial tuberculosis (the causative agent of tuberculosis) and Pseudomonas aeruginosa.^[2]

References

↑ "Activity of lividomycin against Pseudomonas aeruginosa: its inactivation by phosphorylation induced by resistant strains". Antimicrobial Agents and Chemotherapy 1 (1): 17–21. January 1972. doi:10.1128/AAC.1.1.17. PMID 4207755.
↑ "Studies on New Antibiotic Lividomycins. V In vitro and in vivo antimicrobial activity of lividomycin A". The Journal of Antibiotics 25 (2): 128–136. February 1972. doi:10.7164/antibiotics.25.128. PMID 4624613.

0.00

(0 votes)

Original source: https://en.wikipedia.org/wiki/Lividomycin. Read more

Identifiers

IUPAC name (1R,2R,3S,4R,6S)-4,6-Diamino-3-hydroxy-2-{[α-D-mannopyranosyl-(1->4)-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1->3)-β-D-ribofuranosyl]oxy}cyclohexyl 2-amino-2,3-dideoxy-α-D-ribo-hexopyranoside
CAS Number	36441-41-5^Y
PubChem CID	72394
DrugBank	DB04728
ChemSpider	65327
UNII	A606AJ494W
ChEBI	CHEBI:71961^Y
ChEMBL	ChEMBL389029
Chemical and physical data
Formula	C₂₉H₅₅N₅O₁₉
Molar mass	777.775 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O([C@H]4[C@H](O[C@@H]3O[C@H](CO)[C@@H](O[C@H]2O[C@@H](CN)[C@@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O)[C@H](O)[C@H]2N)[C@H]3O)[C@@H](O)[C@H](N)C[C@@H]4N)[C@H]5O[C@@H]([C@@H](O)C[C@H]5N)CO
InChI InChI=1S/C29H55N5O18/c30-3-11-23(51-28-20(43)19(42)17(40)13(5-36)47-28)18(41)15(34)27(45-11)50-24-14(6-37)48-29(21(24)44)52-25-16(39)7(31)1-8(32)22(25)49-26-9(33)2-10(38)12(4-35)46-26/h7-29,35-44H,1-6,30-34H2/t7-,8+,9-,10+,11+,12-,13-,14-,15-,16+,17-,18-,19+,20+,21-,22-,23-,24-,25-,26-,27-,28-,29+/m1/s1 Key:DBLVDAUGBTYDFR-SWMBIRFSSA-N