Chemistry:MRS7292

From HandWiki

MRS7292 is an experimental drug that selectively activates the adenosine A3 receptor with moderate affinity and also inhibits a dopamine reuptake. This combination of mechanisms has been observed in the same molecule.[1][2]

See also

  • MRS8209

References

  1. ↑ "Scaffold Repurposing of Nucleosides (Adenosine Receptor Agonists): Enhanced Activity at the Human Dopamine and Norepinephrine Sodium Symporters". Journal of Medicinal Chemistry 60 (7): 3109–3123. April 2017. doi:10.1021/acs.jmedchem.7b00141. PMID 28319392. 
  2. ↑ "Direct Comparison of (N)-Methanocarba and Ribose-Containing 2-Arylalkynyladenosine Derivatives as A3 Receptor Agonists". ACS Medicinal Chemistry Letters 11 (10): 1935–1941. October 2020. doi:10.1021/acsmedchemlett.9b00637. PMID 33062176. 



Retrieved from "https://handwiki.org/wiki/index.php?title=Chemistry:MRS7292&oldid=4033388"