Chemistry:Maduropeptin
From HandWiki
Short description: Chemical complex
thumb|(−)-Maduropeptin chromophore C-5 methanol adduct
Maduropeptin consists of a 1:1 complex of a carrier protein (MdpA) and a chromophore isolated from Actinomadura madurae.[1] The chromophore has an enediyne structure and is an antibiotic with anticancer activity.[citation needed]
References
- ↑ Ling, J; Horsman, G. P; Huang, S. X; Luo, Y; Lin, S; Shen, B (2010). "Enediyne antitumor antibiotic maduropeptin biosynthesis featuring a C-methyltransferase that acts on a CoA-tethered aromatic substrate". Journal of the American Chemical Society 132 (36): 12534–6. doi:10.1021/ja1050814. PMID 20718468.
External links
 |  |
