Chemistry:Molecular promiscuity

From HandWiki
Short description: Ability of a molecule to bind to interact with one or more other classes and subtypes of molecules

Molecular promiscuity indicates the ability of a molecule to bind to interact with one or more other classes and subtypes of molecules, in synergistic or antagonistic ways. These interactions may involve multiple paracrine, endocrine and autocrine features.[1][2][3]

References

  1. Clark, Adrian JL; Chan, Li F (April 2017). "Promiscuity among the MRAPs". Journal of Molecular Endocrinology 58 (3): F1–F4. doi:10.1530/JME-17-0002. PMID 28213370. 
  2. Barth, Kenneth; Attardo Genco, Caroline (2016). "Microbial Degradation of Cellular Kinases Impairs Innate Immune Signaling and Paracrine TNFα Responses". Scientific Reports 6: 34656. doi:10.1038/srep34656. PMID 27698456. Bibcode2016NatSR...634656B. 
  3. Xiaofeng, Dai; Zhifu, Mao; Songping, Xie; Hao, Zhang; Jie, Huang (January 2013). "The CXCL12/CXCR4 autocrine loop increases the metastatic potential of non-small cell lung cancer in vitro". Oncology Letters 5 (1): 277–282. doi:10.3892/ol.2012.960. PMID 23255935.