Chemistry:N-Phenacylthiazolium bromide

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N-Phenacylthiazolium bromide
N-phenacylthiazolium bromide.svg
Names
Preferred IUPAC name
3-(2-Oxo-2-phenylethyl)-1,3-thiazol-3-ium bromide
Identifiers
3D model (JSmol)
ChemSpider
MeSH C101705
UNII
Properties
C11H10BrNOS
Molar mass 284.17 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

N-Phenacylthiazolium bromide (PTB)[1] is a cross-link breaker that in one study has been shown to prevent vascular advanced glycation end-product accumulation in diabetic rats.[2]

References

  1. Chang, Po-Chun; Tsai, Sheng-Chueh; Chong, Li Yen; Kao, Man-Jung (July 22, 2014). "N-Phenacylthiazolium bromide inhibits the advanced glycation end product (AGE)-AGE receptor axis to modulate experimental periodontitis in rats". Journal of Periodontology 85 (7): e268–276. doi:10.1902/jop.2014.130554. PMID 24988129. 
  2. Cooper, M. E.; Thallas, V; Forbes, J; Scalbert, E; Sastra, S; Darby, I; Soulis, T (2000). "The cross-link breaker, N-phenacylthiazolium bromide prevents vascular advanced glycation end-product accumulation". Diabetologia 43 (5): 660–664. doi:10.1007/s001250051355. PMID 10855541.