Chemistry:Norcamphor
From HandWiki
Norcamphor is an organic compound, classified as a bicyclic ketone. It is an analog of camphor, but without the three methyl groups. A colorless solid, it is used as a building block in organic synthesis.
Synthesis and reactions
Norcamphor was prepared from a Diels-alder reaction of cyclopentadiene and vinyl acetate, followed by oxidation with chromic acid in acetic acid solution. A more recent synthesis produces norbornene via the 2-formate ester, oxidized with chromic acid in acetone. It is a precursor to norborneols.[1] The enzymatically mediated Baeyer-Villiger oxidation of norcamphor gives the lactone.[2]
See also
References
- ↑ Kleinfelter, Donald C.; Schleyer, Paul von R. (1962). "2-Norbornanone". Org. Synth. 42: 79. doi:10.15227/orgsyn.042.0079.
- ↑ Leisch, Hannes; Morley, Krista; Lau, Peter C. K. (2011). "Baeyer−Villiger Monooxygenases: More Than Just Green Chemistry". Chemical Reviews 111 (7): 4165–4222. doi:10.1021/cr1003437. PMID 21542563.
