Chemistry:Oxathiapiprolin

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Oxathiapiprolin
Oxathiapiprolin skeletal.svg
Names
Preferred IUPAC name
12,16-Difluoro-75-methyl-73-(trifluoromethyl)-24,25-dihydro-4(4,1)-piperidina-2(5,3)-[1,2]oxazola-3(4,2)-[1,3]thiazola-7(1)-pyrazola-1(1)-benzenaheptaphan-5-one
Identifiers
3D model (JSmol)
UNII
Properties
C24H22F5N5O2S
Molar mass 539.53 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

Oxathiapiprolin (trade names Orondis,[1] Zorvec, and Segovis) is a fungicide. In the United States, the Environmental Protection Agency has approved it for use against several fungal diseases including downy mildew and various Phytophthora species[1] including late blight on crops including vegetables, ornamentals, and turf.[2]

Its mechanism of action involves binding to the oxysterol-binding protein in Oomycetes.[3][4]

References

  1. 1.0 1.1 "Orondis - Fungicide Product & Label Information" (in en). http://www.syngenta-us.com/fungicides/orondis. 
  2. "Oxathiapiprolin". New Active Ingredient Review. Minnesota Department of Agriculture. October 2015. http://www.mda.state.mn.us/chemicals/pesticides/regs/~/media/Files/chemicals/reviews/nair-oxathiapiprolin.pdf. 
  3. Cohen, Yigal (2015). "The Novel Oomycide Oxathiapiprolin Inhibits All Stages in the Asexual Life Cycle of Pseudoperonospora cubensis - Causal Agent of Cucurbit Downy Mildew". PLOS ONE 10 (10): e0140015. doi:10.1371/journal.pone.0140015. PMID 26452052. Bibcode2015PLoSO..1040015C. 
  4. Pasteris, Robert J; Hanagan, Mary Ann; Bisaha, John J; Finkelstein, Bruce L; Hoffman, Lisa E; Gregory, Vann; Shepherd, Christopher P; Andreassi, John L et al. (2015). "The Discovery of Oxathiapiprolin: A New, Highly-Active Oomycete Fungicide with a Novel Site of Action". Discovery and Synthesis of Crop Protection Products. ACS Symposium Series. 1204. pp. 149. doi:10.1021/bk-2015-1204.ch011. ISBN 978-0-8412-3102-3.