Chemistry:PIPE-359
From HandWiki
PIPE-359 is an experimental drug that acts as a potent and selective antagonist of the muscarinic acetylcholine receptor M1. It has been investigated for potential application in remyelination of nerve sheaths for the treatment of multiple sclerosis.[1]
References
- ↑ "Discovery of PIPE-359, a Brain-Penetrant, Selective M1 Receptor Antagonist with Robust Efficacy in Murine MOG-EAE". ACS Medicinal Chemistry Letters 12 (1): 155–161. January 2021. doi:10.1021/acsmedchemlett.0c00626. PMID 33488977.
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