Chemistry:PSB-KD107
From HandWiki
PSB-KD107 is an experimental drug that acts as a potent and selective agonist for the cannabinoid-like NAGly receptor, also known as GPR18. It has antiinflammatory effects, and has been studied in an animal model of Duchenne muscular dystrophy.[1][2]
References
- ↑ "Discovery of Tricyclic Xanthines as Agonists of the Cannabinoid-Activated Orphan G-Protein-Coupled Receptor GPR18". ACS Medicinal Chemistry Letters 11 (10): 2024–2031. October 2020. doi:10.1021/acsmedchemlett.0c00208. PMID 33062188.
- ↑ "Gpr18 agonist dampens inflammation, enhances myogenesis, and restores muscle function in models of Duchenne muscular dystrophy". Frontiers in Cell and Developmental Biology 11. 2023. doi:10.3389/fcell.2023.1187253. PMID 37645248.
 |  |
