Chemistry:Phenylaminotetralin

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Phenylaminotetralin
(-)-trans-H2-PAT Structure.svg
Names
IUPAC name
(2S,4R)-N,N-dimethyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-2-amine
Identifiers
3D model (JSmol)
ChemSpider
Properties
C18H21N
Molar mass 251.373 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Phenylaminotetralins are novel histamine receptor ligands. Binding assays determined that (-)-trans-H2-PAT possessed the strongest binding affinity at the histamine H1 receptor.[1]

References

  1. Booth, RG; Moniri, NH; Bakker, RA; Choksi, NY; Nix, WB; Timmerman, H; Leurs, R (July 2002). "A novel phenylaminotetralin radioligand reveals a subpopulation of histamine H(1) receptors". The Journal of Pharmacology and Experimental Therapeutics 302 (1): 328–36. doi:10.1124/jpet.302.1.328. PMID 12065734.