Chemistry:Procysteine
From HandWiki
Procysteine is an organic compound with the formula CH
2NHC(O)SCHCO
2H. It is a colorless solid. The compound is classified as a derivative of the heterocycle 2-oxo-1,3-thiazoline. Such rings are prepared by the action of phosgene (or related dehydration reagents[1] on 2-aminoethanethiols, in this case cysteine:
- HSCH
2CH(NH
2)CO
2H + COCl
2 → CH
2NHC(O)SCHCO
2H + 2 HCl
The compound hydrolyzes to cysteine.[2] The hydrolysis is catalyzed by 5-oxoprolinase.[1]
References
- ↑ 1.0 1.1 Boettcher, Brian; Meister, Alton (1984). "Synthesis of l -2-oxothiazolidine-4-carboxylic acid". Analytical Biochemistry 138 (2): 449–450. doi:10.1016/0003-2697(84)90837-6. PMID 6742422.
- ↑ Anderson, Mary E. (1998). "Glutathione: An overview of biosynthesis and modulation". Chemico-Biological Interactions 111-112: 1–14. doi:10.1016/S0009-2797(97)00146-4. PMID 9679538. Bibcode: 1998CBI...111....1A.
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