Chemistry:Rezuforimod
From HandWiki
Rezuforimod is an experimental drug that acts as a potent and selective agonist of formyl peptide receptor 2 with an EC50 of 0.88nM, which inhibits neutrophil adhesion and has antiinflammatory effects.[1][2]
References
- ↑ "Recent advances in the design and development of formyl peptide receptor 2 (FPR2/ALX) agonists as pro-resolving agents with diverse therapeutic potential". European Journal of Medicinal Chemistry 213. March 2021. doi:10.1016/j.ejmech.2021.113167. PMID 33486199.
- ↑ "Synthesis and evaluation of novel cyclopentane urea FPR2 agonists and their potential application in the treatment of cardiovascular inflammation". European Journal of Medicinal Chemistry 214. March 2021. doi:10.1016/j.ejmech.2021.113194. PMID 33548634.
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