Chemistry:Sisunatovir
From HandWiki
Sisunatovir is an investigational new drug that is being evaluated for the treatment of respiratory syncytial virus (RSV) infections.[1] It functions as an orally administered RSV fusion inhibitor, targeting the RSV-F protein on the viral surface to prevent viral replication.[2] Sisunatovir has been granted Fast Track designation by the U.S. Food and Drug Administration (FDA) due to its potential to address serious RSV infections, which can lead to severe respiratory conditions such as bronchiolitis and pneumonia.[3]
References
- โ "Sisunatovir - ReViral". AdisInsight. Springer Nature Switzerland AG. https://adisinsight.springer.com/drugs/800049439.
- โ "Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion". Journal of Medicinal Chemistry 64 (7): 3658โ3676. April 2021. doi:10.1021/acs.jmedchem.0c01882. PMID 33729773. https://orca.cardiff.ac.uk/id/eprint/143067/1/jm-2020-01882r.R2_Proof_hi.pdf.
- โ "Sisunatovir Fast-Tracked for Serious RSV Infection". Medical Professionals Network. Haymarket Media, Inc.. 6 August 2020. https://www.empr.com/home/news/drugs-in-the-pipeline/sisunatovir-orally-administered/.
