Chemistry:Smash Childhood Cancer
Smash Childhood Cancer is a World Community Grid volunteer computing subproject on the BOINC platform.[1] It is based on World Community Grid's Help Childhood Cancer subproject which was a joint effort of Chiba University and the Chiba Cancer Center.[2] Based on the results of that project,[3] the Smash Childhood Cancer started in January 2017 looking for drug candidates targeting additional childhood cancers.[4]
Project Purpose
Neuroblastoma is the most common type of solid tumor which afflicts children. Three different proteins have been implicated in the production of neuroblastoma. If these proteins can be disabled, conventional treatments would be much more effective. Medicinal chemists have identified three million different molecules which might disable the proteins. Treating it as a problem in ligand docking, a computer program called AutoDock will virtually attempt to fit each molecule to each protein in such a way that the protein is disabled.[5]
See also
- BOINC
- List of volunteer computing projects
- World Community Grid
- Band of Parents
- The Neuroblastoma Society
- Neuroblastoma Children's Cancer Alliance UK
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Wikimedia Commons has media related to Smash Childhood Cancer. |
References
- ↑ "Smash Childhood Cancer (paused) :: Project Delve". https://projectdelve.com/computational/smash-childhood-cancer/.
- ↑ "Chiba Cancer Center". http://www.chiba-cc.jp/en/index.html.
- ↑ "The Road Ahead for Help Fight Childhood Cancer" (in en-US). https://www.worldcommunitygrid.org/about_us/viewNewsArticle.do?articleId=537.
- ↑ "Researchers Reunite with World Community Grid to Smash Childhood Cancer" (in en-US). https://www.worldcommunitygrid.org/about_us/viewNewsArticle.do?articleId=512.
- ↑ "Help Fight Childhood Cancer". https://secure.worldcommunitygrid.org/research/hfcc/details.do.
External links
- Help Fight Childhood Cancer official site
- Help Fight Childhood Cancer, World Community Grid
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