Chemistry:TAN-1057 C

From HandWiki
TAN-1057 C and TAN-1057 D
TAN-1057 C
TAN-1057 C
TAN-1057 D
TAN-1057 D
Identifiers
3D model (JSmol)
ChemSpider
UNII
Properties
C13H25N9O3
Molar mass 355.403 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

TAN-1057 C and TAN-1057 D are organic compounds found in the Flexibacter sp. PK-74 bacterium. TAN-1057 C and D are closely related structurally as diastereomers. Also related are TAN-1057 A and TAN-1057 B, isolated from the same bacteria. The four compounds have been shown to be an effective antibiotics against methicillin-resistant strains of Staphylococcus aureus which act through the inhibition of protein biosynthesis.[1]

References

  1. Katayama, N (1993). "TAN-1057 A-D, new antibiotics with potent antibacterial activity against methicillin-resistant Staphylococcus aureus. Taxonomy, fermentation and biological activity". J. Antibiot. 46 (4): 606–613. doi:10.7164/antibiotics.46.606. PMID 8501003.