Chemistry:WAY-213,613
From HandWiki
Short description: Chemical compound
![]() | |
Identifiers | |
---|---|
| |
CAS Number | |
PubChem CID | |
IUPHAR/BPS | |
ChemSpider | |
UNII | |
ChEMBL | |
Chemical and physical data | |
Formula | C16H13BrF2N2O4 |
Molar mass | 415.191 g·mol−1 |
3D model (JSmol) | |
| |
| |
![]() ![]() |
WAY-213,613 is a drug which acts as a reuptake inhibitor for the glutamate transporter subtype EAAT2, selective over other glutamate transporter subtypes and highly selective over metabotropic and ionotropic glutamate receptors.[1] It is used in scientific research into the function of the glutamate transporters.[2]
References
- ↑ "Characterization of novel aryl-ether, biaryl, and fluorene aspartic acid and diaminopropionic acid analogs as potent inhibitors of the high-affinity glutamate transporter EAAT2". Molecular Pharmacology 68 (4): 974–82. October 2005. doi:10.1124/mol.105.012005. PMID 16014807.
- ↑ "Protein kinase C-dependent trafficking of glutamate transporters excitatory amino acid carrier 1 and glutamate transporter 1b in cultured cerebellar granule cells". Neuroscience 161 (3): 794–805. July 2009. doi:10.1016/j.neuroscience.2009.04.017. PMID 19364521.
![]() | Original source: https://en.wikipedia.org/wiki/WAY-213,613.
Read more |