Chemistry:Wrightiadione
From HandWiki
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| Preferred IUPAC name
Indeno[2,1-b][1]benzopyran-6,11-dione | |
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3D model (JSmol)
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PubChem CID
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| Properties | |
| C16H8O3 | |
| Molar mass | 248.237 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Tracking categories (test):
Wrightiadione is an isoflavone that occurs in the plant Wrightia tomentosa[1] and can also be synthesized.[2][3] It is a novel template for the TrkA kinase inhibitors.[4]
References
- ↑ Lin, Topcu, Lotter, Ruangrunsi, Wagner, Pezzuto and Cordell (1992). "Wrightiadione from Wrightia Tomentosa". Phytochemistry 31 (12): 4333–4335. doi:10.1016/0031-9422(92)80469-U.
- ↑ Ruschirawat and Thasana (2001). "The First Synthesis of Wrightiadione". Synthetic Communications 31 (11): 1765–1769. doi:10.1081/SCC-100104406.
- ↑ *"Tandem Dehydrogenation/Oxidation/Oxidative Cyclization Approach to Wrightiadione and Its Derivatives". Org Lett 17 (13): 3252–5. 2015. doi:10.1021/acs.orglett.5b01618. PMID 26090926.
- ↑ "Discovery of wrightiadione as a novel template for the TrkA kinase inhibitors". Bioorg Med Chem Lett 25 (22): 5186–9.. 2015. doi:10.1016/j.bmcl.2015.09.070. PMID 26442778.
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