Chemistry:Zeteletinib

Zeteletinib
Identifiers
	IUPAC name 2-[6-(6,7-dimethoxyquinolin-3-yl)pyridin-3-yl]-N-[3-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-5-yl]acetamide;
CAS Number	2216753-97-6 [UNII];
PubChem CID	134391533;
ChemSpider	115007145;
UNII	EP0P7SHM0U;
ChEMBL	ChEMBL5095497;
Chemical and physical data
Formula	C25H23F3N4O4
Molar mass	500.478 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)(C1=NOC(=C1)NC(=O)CC2=CN=C(C=C2)C3=CN=C4C=C(C(=CC4=C3)OC)OC)C(F)(F)F;
	InChI InChI=1S/C25H23F3N4O4/c1-24(2,25(26,27)28)21-11-23(36-32-21)31-22(33)7-14-5-6-17(29-12-14)16-8-15-9-19(34-3)20(35-4)10-18(15)30-13-16/h5-6,8-13H,7H2,1-4H3,(H,31,33); Key:KOLQINCWMXQEOF-UHFFFAOYSA-N;

Short description: Chemical compound

Zeteletinib (BOS-172738, DS-5010) is an experimental anticancer medication which acts as a RET inhibitor.^[1]^[2]

References

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Original source: https://en.wikipedia.org/wiki/Zeteletinib. Read more

Identifiers

IUPAC name 2-[6-(6,7-dimethoxyquinolin-3-yl)pyridin-3-yl]-N-[3-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-5-yl]acetamide
CAS Number	2216753-97-6^Y[UNII]
PubChem CID	134391533
ChemSpider	115007145
UNII	EP0P7SHM0U
ChEMBL	ChEMBL5095497
Chemical and physical data
Formula	C₂₅H₂₃F₃N₄O₄
Molar mass	500.478 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC(C)(C1=NOC(=C1)NC(=O)CC2=CN=C(C=C2)C3=CN=C4C=C(C(=CC4=C3)OC)OC)C(F)(F)F
InChI InChI=1S/C25H23F3N4O4/c1-24(2,25(26,27)28)21-11-23(36-32-21)31-22(33)7-14-5-6-17(29-12-14)16-8-15-9-19(34-3)20(35-4)10-18(15)30-13-16/h5-6,8-13H,7H2,1-4H3,(H,31,33) Key:KOLQINCWMXQEOF-UHFFFAOYSA-N