File:Nigral-proteasome-inhibition-in-mice-leads-to-motor-and-non-motor-deficits-and-increased-expression-Video1.ogv

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Description
English: “Behavioral despair” in the tail suspension test. After a period of initial struggle, control mice demonstrate intervals of immobile behavior, reflecting reluctance to maintain active escape-oriented behavior. Indicated is a representative 1 min interval from the tail suspension test of a sham-treated mouse (trial period: 2 min 30 s—3min 30 s), during which the mouse shows primarily immobile behavior. The video is shown at 4x its normal speed.
Date
Source Supplementary Video 1 from Bentea E, Van der Perren A, Van Liefferinge J, El Arfani A, Albertini G, Demuyser T, Merckx E, Michotte Y, Smolders I, Baekelandt V, Massie A (2015). "Nigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated α-synuclein". Frontiers in Behavioral Neuroscience. DOI:10.3389/fnbeh.2015.00068. PMID 25873870. PMC: 4379937.
Author Bentea E, Van der Perren A, Van Liefferinge J, El Arfani A, Albertini G, Demuyser T, Merckx E, Michotte Y, Smolders I, Baekelandt V, Massie A
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Tail suspension test : after a period of initial struggle, control mice demonstrate intervals of immobile behavior, reflecting reluctance to maintain active escape-oriented behavior. The video is shown at 4x its normal speed.

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31 March 2015

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