Medicine:21st Century Medicine

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Short description: Cryobiological research company

21st Century Medicine (21CM) is a California cryobiological research company which has as its primary focus the development of perfusates and protocols for viable long-term cryopreservation of human organs, tissues and cells at temperatures below −100 °C through the use of vitrification. 21CM was founded in 1993.

In 2004 21CM received a $900,000 grant from the U.S. National Institutes of Health (NIH) to study a preservation solution developed by the University of Rochester in New York for extending simple cold storage time of human hearts removed for transplant.[1]

At the July 2005 annual conference of the Society for Cryobiology, 21st Century Medicine announced the vitrification of a rabbit kidney to −135 °C with their vitrification mixture. The kidney was successfully transplanted upon rewarming to a rabbit, the rabbit being euthanized on the 48th day for histological follow-up.[2][3]

On February 9, 2016, 21st Century Medicine won the Small Mammal Brain Preservation Prize.[4] On March 13, 2018, they won the Large Mammal Brain Preservation Prize.[5]

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