Medicine:Baboon syndrome
| Baboon syndrome | |
|---|---|
| Specialty | Dermatology |
Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE), popularly known as baboon syndrome because of its resemblance to the distinctive red buttocks displayed by female baboons, is a systemic dermatitis characterized by well-demarcated patches of erythema distributed symmetrically on the buttocks.[1] The cause of the syndrome may be drug-related: i.e., induced by systemic administration of hydroxyzine,[2] penicillin,[3] iodinated radio contrast media,[4] and others.
Symptoms and signs
The typical rash commonly appears on buttocks. This then resembles the colour of a baboon's buttocks. Other areas like upper inner thigh and armpits, may be affected by the rash. The rashes are red and well-defined. The presentation is typically symmetrical and not associated with systemic symptoms.[5]
Cause
Diagnosis
Treatment
Treatment of symmetrical drug related intertriginous and flexural exanthema involves identifying and stopping the causative agent. Topical steroids can help to reduce the redness.[6]
Epidemiology
Baboon syndrome affects both sexes equally, and can occur at any age, but seems to be more common in childhood than in adulthood.[7]
See also
- Airbag dermatitis
- List of cutaneous conditions
References
- ↑ Dermatology: 2-Volume Set. St. Louis: Mosby. 2007. ISBN 978-1-4160-2999-1.
- ↑ "Baboon syndrome induced by hydroxyzine". Indian Journal of Dermatology 58 (3): 244. May 2013. doi:10.4103/0019-5154.110871. PMID 23723506.
- ↑ "SDRIFE (baboon syndrome) induced by penicillin". Clinical and Experimental Dermatology 34 (3): 355–357. April 2009. doi:10.1111/j.1365-2230.2008.02911.x. PMID 18699835.
- ↑ "Recurrent flexural exanthema (SDRIFE or baboon syndrome) after administration of two different iodinated radio contrast media". Dermatology 214 (1): 89–93. 2007. doi:10.1159/000096920. PMID 17191055.
- ↑ "Baboon syndrome and segmental vitiligo coexistence". The Turkish Journal of Pediatrics 51 (4): 392–394. 2009. PMID 19950853.
- ↑ "Symmetrical drug related intertriginous and flexural exanthema". DermNet NZ. https://www.dermnetnz.org/topics/symmetrical-drug-related-intertriginous-and-flexural-exanthema/.
- ↑ "Baboon syndrome in childhood: easy to avoid, easy to diagnose, but the problem continues". Pediatric Dermatology 21 (3): 250–253. 2004. doi:10.1111/j.0736-8046.2004.21313.x. PMID 15165206.
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