Medicine:Bovine Meat and Milk Factors

From HandWiki

Bovine Meat and Milk Factors (BMMFs) are DNA molecules found in beef and cow's milk which have been linked to the development of cancer—particularly colorectal and breast cancer.[1]

Research

The potential connection between BMMFs and cancer has been made based on assessments of epidemiological data[2][3][4] and the investigation of antibodies in human serum.[5][6] Research has also suggested a potential link between BMMFs and neurodegenerative diseases such as multiple sclerosis.[5]

At the end of 2017, evidence was presented that BMMFs in human cells show long-term survival, through the identification of BMMFs' RNA and protein products.[5][7] In February 2019, evidence was presented of a previously unknown infectious agent in the blood serum and milk of Eurasian cattle that could indirectly trigger the development of colorectal cancer.[3]

References

  1. ↑ "Episomal-Persistent DNA in Cancer- and Chronic Diseases". https://www.dkfz.de/en/episomal-persistierende-DNA/groups/Research.html. 
  2. ↑ Hausen, Harald zur; Villiers, Ethel-Michele de (2015). "Dairy cattle serum and milk factors contributing to the risk of colon and breast cancers" (in en). International Journal of Cancer 137 (4): 959–67. doi:10.1002/ijc.29466. ISSN 1097-0215. PMID 25648405. 
  3. ↑ 3.0 3.1 Hausen, Harald zur; Bund, Timo; Villiers, Ethel-Michele de (2019). "Specific nutritional infections early in life as risk factors for human colon and breast cancers several decades later" (in en). International Journal of Cancer 144 (7): 1574–1583. doi:10.1002/ijc.31882. ISSN 1097-0215. PMID 30246328. 
  4. ↑ Däuble, Wolfgang. "Nobelpreisträger zur Hausen: Warum haben Inder so selten Darmkrebs?" (in de). FAZ.NET. ISSN 0174-4909. https://www.faz.net/1.2904246. 
  5. ↑ 5.0 5.1 5.2 Eilebrecht, Sebastian; Hotz-Wagenblatt, Agnes; Sarachaga, Victor; Burk, Amelie; Falida, Konstantina; Chakraborty, Deblina; Nikitina, Ekaterina; Tessmer, Claudia et al. (2018-02-12). "Expression and replication of virus-like circular DNA in human cells" (in en). Scientific Reports 8 (1): 2851. doi:10.1038/s41598-018-21317-w. ISSN 2045-2322. PMID 29434270. Bibcode: 2018NatSR...8.2851E. 
  6. ↑ "Erhöhtes Krebsrisiko durch Kuhmilch und Rindfleisch?" (in de). 23 October 2018. https://www.aerztezeitung.de/Medizin/Erhoehtes-Krebsrisiko-durch-Kuhmilch-und-Rindfleisch-224843.html. 
  7. ↑ "Episomal-Persistierende DNA in Krebs- und chronischen Erkrankungen". https://www.dkfz.de/de/episomal-persistierende-DNA/index.php. 

Further reading

  • Falida, Konstantina (2019-12-11). Identification of single-stranded DNAs from beef products, their replication in human cells and their relationship with breast cancer (DSc thesis). Heidelberg University.




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