Medicine:Casoni test
| Casoni test | |
|---|---|
| Medical diagnostics | |
| Purpose | diagnosis of hydatid disease |
The Casoni test is a skin test used in the diagnosis of hydatid disease. The test involves the intradermal injection of 0.25 ml of sterilised fluid from hydatid cysts/human cyst and sterilised by Seitz filtration on forearm and equal volume of saline injected on the other forearm. Observations made for next 30 mins and after 1 to 2 days.[1] A wheal response occurring at the injection site within 20 minutes is considered positive (immediate hypersensitivity). Delayed hypersensitivity reactions usually read after 18–24 hours.[2] The test is positive in about 90% of cases of hydatid disease affecting the liver, but positive in less than 50% of patients with hydatid disease elsewhere in the body; false positive results are also common. Being a type I hypersensitivity reaction, anaphylactic reaction tray must be kept ready before carrying out the test.[3] Consequently, serological tests are now generally used.[4] The test was described in 1912 by Tomaso Casoni.[5]
References
- ↑ "Casoni's Test". http://microbiology.4umer.net/t88-casoni-s-test.
- ↑ Robert A. Evans. Special Tests: The Procedure and Meaning of the Commoner Tests in Hospital, page 14. Elsevier Health Sciences, 2003. ISBN:978-0-7234-3289-0.
- ↑ "Casoni's Test". http://microbiology.4umer.net/t88-casoni-s-test.
- ↑ Richard Ravel. Clinical laboratory medicine, page 291. Elsevier Health Sciences, 1994. ISBN:978-0-8151-7148-5.
- ↑ Casoni T. La diagnosi biologica dell'echinococcosi umana mediante l'introdermoreazione. Folia Clinica Chimica e Microscopica; 1912: 4
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