Medicine:Chronic histiocytic intervillositis
From HandWiki
| Chronic histiocytic intervillositis | |
|---|---|
| Specialty | OB/GYN |
Chronic Histiocytic Intervillositis (CHI or CHIV) also known as Chronic Intervillositis of Unknown (A)etiology (CIUE) and Massive Chronic Intervillositis (MCI) is defined as a diffuse infiltration of mononuclear cells (histiocytes, lymphocytes, monocytes) of maternal origin into the intervillous space within the placenta. It often results in severe intrauterine growth restriction which can lead to miscarriage or stillbirth. Overall perinatal mortality rate is high: 41%.[1] to 77%.[2] Recurrence rate is also high: 67%[2] to 100%[1]
References
- ↑ 1.0 1.1 "Chronic intervillositis of unknown etiology (CIUE): relation between placental lesions and perinatal outcome.". European Journal of Obstetrics, Gynecology, and Reproductive Biology 143: 9-13. doi:10.1016/j.ejogrb.2008.06.012. PMID 19121887.
- ↑ 2.0 2.1 "Chronic histiocytic intervillositis: A placental lesion associated with recurrent reproductive loss.". Human Pathology 31: 1389–96. doi:10.1016/s0046-8177(00)80009-x. PMID 11112214.
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