Medicine:Stillbirth

From HandWiki
Short description: Death of a fetus before or during delivery, resulting in delivery of a dead baby
Stillbirth
Other namesFetal death, fetal demise[1]
Nuchal edema in Down Syndrome Dr. W. Moroder.jpg
Ultrasound is often used to diagnose stillbirth and medical conditions that raise the risk.
SpecialtyGynaecology Neonatology Pediatrics Obstetrics
SymptomsFetal death at or after 20 / 28 weeks of pregnancy[1][2]:{{{1}}}
CausesOften unknown, pregnancy complications[1][3]
Risk factorsMother's age over 35, smoking, drug use, use of assisted reproductive technology[4]
Diagnostic methodNo fetal movement felt, ultrasound[5]
TreatmentInduction of labor, dilation and evacuation[6]
Frequency1.9 million (1 for every 72 total births)[7]

Stillbirth is typically defined as fetal death at or after 20 or 28 weeks of pregnancy, depending on the source.[1][2]:{{{1}}}[8] It results in a baby born without signs of life.[9] A stillbirth can often result in the feeling of guilt or grief in the mother.[10] The term is in contrast to miscarriage, which is an early pregnancy loss,[11] and Sudden Infant Death Syndrome, where the baby dies a short time after being born alive.[10]

Often the cause is unknown.[1][12] Causes may include pregnancy complications such as pre-eclampsia and birth complications, problems with the placenta or umbilical cord, birth defects, infections such as malaria and syphilis, and poor health in the mother.[2]:{{{1}}}[3][13] Risk factors include a mother's age over 35, smoking, drug use, use of assisted reproductive technology, and first pregnancy.[4] Stillbirth may be suspected when no fetal movement is felt.[5] Confirmation is by ultrasound.[5]

Worldwide prevention of most stillbirths is possible with improved health systems.[2]:{{{1}}}[14] Around half of stillbirths occur during childbirth, with this being more common in the developing than developed world.[2]:{{{1}}} Otherwise, depending on how far along the pregnancy is, medications may be used to start labor or a type of surgery known as dilation and evacuation may be carried out.[6] Following a stillbirth, women are at higher risk of another one; however, most subsequent pregnancies do not have similar problems.[15] Depression, financial loss, and family breakdown are known complications.[14]

Worldwide in 2021, there were an estimated 1.9 million stillbirths that occurred after 28 weeks of pregnancy (about 1 for every 72 births).[16] More than three-quarters of estimated stillbirths in 2021 occurred in sub-Saharan Africa and South Asia, with 47% of the global total in sub-Saharan Africa and 32% in South Asia.[17] Stillbirth rates have declined, though more slowly since the 2000s.[18] According to UNICEF, the total number of stillbirths declined by 35%, from 2.9 million in 2000 to 1.9 million in 2021.[16] It is estimated that if the stillbirth rate for each country stays at the 2021 level, 17,5 million babies will be stillborn by 2030.[16]

Causes

As of 2016, there is no international classification system for stillbirth causes.[19] The causes of a large percentage of stillbirths is unknown, even in cases where extensive testing and an autopsy have been performed. A rarely used term to describe these is "sudden antenatal death syndrome", or SADS, a phrase coined in 2000.[20] Many stillbirths occur at full term to apparently healthy mothers, and a postmortem evaluation reveals a cause of death in about 40% of autopsied cases.[21]

About 10% of cases are believed to be due to obesity, high blood pressure, or diabetes.[22]

Other risk factors include:

Entanglement of cord in twin pregnancy at the time of Caesarean section
  • umbilical cord accidents
    • Prolapsed umbilical cord – Prolapse of the umbilical cord happens when the fetus is not in a correct position in the pelvis. Membranes rupture and the cord is pushed out through the cervix. When the fetus pushes on the cervix, the cord is compressed and blocks blood and oxygen flow to the fetus. The mother has approximately 10 minutes to get to a doctor before there is any harm done to the fetus.
    • Monoamniotic twins – These twins share the same placenta and the same amniotic sac and therefore can interfere with each other's umbilical cords. When entanglement of the cords is detected, it is highly recommended to deliver the fetuses as early as 31 weeks.
    • Umbilical cord length – A short umbilical cord (<30 cm) can affect the fetus in that fetal movements can cause cord compression, constriction, and rupture. A long umbilical cord (>72 cm) can affect the fetus depending on the way the fetus interacts with the cord.[26] Some fetuses grasp the umbilical cord but it is yet unknown as to whether a fetus is strong enough to compress and stop blood flow through the cord. Also, an active fetus, one that frequently repositions itself in the uterus can accidentally entangle itself with the cord. A hyperactive fetus should be evaluated with ultrasound to rule out cord entanglement.
    • Cord entanglement – The umbilical cord can wrap around an extremity, the body or the neck of the fetus. When the cord is wrapped around the neck of the fetus, it is called a nuchal cord. These entanglements can cause constriction of blood flow to the fetus. These entanglements can be visualized with ultrasound.
    • Torsion – This term refers to the twisting of the umbilical around itself. Torsion of the umbilical cord is very common (especially in equine stillbirths) but it is not a natural state of the umbilical cord. The umbilical cord can be untwisted at delivery. The average cord has three twists.
  • Smoke inhalation – If a pregnant woman gets trapped in a building fire, the smoke and fumes can kill an unborn child.[citation needed]

A pregnant woman sleeping on her back after 28 weeks of pregnancy may be a risk factor for stillbirth.[22][27]

After a stillbirth there is a 2.5% risk of another stillbirth in the next pregnancy (an increase from 0.4%).[28]

In the United States, highest rates of stillbirths happen in pregnant women who:[29]

  • are of low socioeconomic status
  • are aged 35 years or older
  • have chronic medical conditions such as diabetes, high blood pressure, high cholesterol, etc.
  • are African-American
  • have previously lost a child during pregnancy
  • have multiple children at a time (twins, triplets, etc.)

Diagnosis

It is unknown how much time is needed for a fetus to die. Fetal behavior is consistent and a change in the fetus' movements or sleep-wake cycles can indicate fetal distress.[30] A decrease or cessation in sensations of fetal activity may be an indication of fetal distress or death,[31] though it is not entirely uncommon for a healthy fetus to exhibit such changes, particularly near the end of a pregnancy when there is considerably less space in the uterus than earlier in pregnancy for the fetus to move about.[32] Still, medical examination, including a nonstress test, is recommended in the event of any type of any change in the strength or frequency of fetal movement, especially a complete cease; most midwives and obstetricians recommend the use of a kick chart to assist in detecting any changes.[33] Fetal distress or death can be confirmed or ruled out via fetoscopy/doptone, ultrasound, and/or electronic fetal monitoring.[34] If the fetus is alive but inactive, extra attention will be given to the placenta and umbilical cord during ultrasound examination to ensure that there is no compromise of oxygen and nutrient delivery.[35]

Some researchers have tried to develop models to identify, early on, pregnant women who may be at high risk of having a stillbirth.[36]

Definition

There are a number of definitions for stillbirth.[37] To allow comparison, the World Health Organization uses the ICD-10 definitions and recommends that any baby born without signs of life at greater than or equal to 28 completed weeks' gestation be classified as a stillbirth.[2]:{{{1}}} The WHO uses the ICD-10 definitions of "late fetal deaths" as their definition of stillbirth.[18] Other organisations recommend that any combination of greater than 16, 20, 22, 24 or 28 weeks gestational age or 350 g, 400 g, 500 g or 1000 g birth weight may be considered a stillbirth.[38]

The term is often used in distinction to live birth (the baby was born alive, even if they died shortly thereafter) or miscarriage (early pregnancy loss[37]). The word miscarriage is often used incorrectly to describe stillbirths.[37] The term is mostly used in a human context; however, the same phenomenon can occur in all species of placental mammals.

Constricted umbilical cord

When the umbilical cord is constricted (q.v. "accidents" above), the fetus experiences periods of hypoxia, and may respond by unusually high periods of kicking or struggling, to free the umbilical cord.[39] These are sporadic if constriction is due to a change in the fetus' or mother's position, and may become worse or more frequent as the fetus grows.[40] Extra attention should be given if mothers experience large increases in kicking from previous childbirths, especially when increases correspond to position changes.[41]

Regulating high blood pressure, diabetes and drug use may reduce the risk of a stillbirth. Umbilical cord constriction may be identified and observed by ultrasound, if requested.[42]

Some maternal factors are associated with stillbirth, including being age 35 or older, having diabetes, having a history of addiction to illegal drugs, being overweight or obese, and smoking cigarettes in the three months before getting pregnant.[43]

Treatment

A cuddle cot.

Fetal death in utero does not present an immediate health risk to the pregnant woman, and labour will usually begin spontaneously after two weeks, so the pregnant woman may choose to wait and bear the fetal remains vaginally.[44] After two weeks, the pregnant woman is at risk of developing blood clotting problems, and labor induction is recommended at this point.[45] In many cases, the pregnant woman will find the idea of carrying the dead fetus traumatizing and will elect to have labor induced. Caesarean birth is not recommended unless complications develop during vaginal birth.[46] How the diagnosis of stillbirth is communicated by healthcare workers may have a long-lasting and deep impact on parents.[47] People need to heal physically after a stillbirth just as they do emotionally. In Ireland, for example, people are offered a 'cuddle cot', a cooled cot which allows them to spend a number of days with their child before burial or cremation.[48] In a number of locations, including some states in the United States, physicians will refuse to extract the body of the stillborn fetus, as it is considered an abortion and therefore illegal in those jurisdictions.

Delivery

In single stillbirths, common practice is to induce labor for the health of the mother due to possible complications such as exsanguination. Induction and labor can take 48 hours.[37] In the case of various complications such as preclampsia, infections, multiples(twins), emergency Cesarean may occur.[49]

Epidemiology

The average stillbirth rate in the United States is approximately 1 in 160 births, which is roughly 26,000 stillbirths each year.[50] In Australia,[51] England, Wales,[52][53] and Northern Ireland,[54] the rate is approximately 1 in every 200 births; in Scotland, 1 in 167.[55] Rates of stillbirth in the United States have decreased by about two-thirds since the 1950s.[56]

The vast majority of stillbirths worldwide (98%) occur in low- and middle-income countries, where medical care can be of low quality or unavailable. Reliable estimates calculate that, yearly, about 2.6 million stillbirths occur worldwide during the third trimester.[13] Stillbirths were previously not included in the Global Burden of Disease Study which records worldwide deaths from various causes until 2015.[57]

Society and culture

The way people view stillbirths has changed dramatically over time; however, its economic and psychosocial impact is often underestimated.[58] In the early 20th century, when a stillbirth occurred, the baby was taken and discarded and the parents were expected to immediately let go of the attachment and try for another baby.[59][page needed] In many countries, parents are expected by friends and family members to recover from the loss of an unborn baby very soon after it happens.[21] Societally-mediated complications such as financial hardship and depression are among the more common results.[21] A stillbirth can have significant psychological effects on the parents, notably causing feelings of guilt in the mother.[10] Further psycho-social effects on parents include apprehension, anger, feelings of worthlessness and not wanting to interact with other people, with these reactions sometimes carried over into pregnancies that occur after the stillbirth.[60] Men also suffer psychologically after stillbirth, although they are more likely to hide their grief and feelings and try to act strong, with the focus on supporting their partner.[61]

Legal definitions

In Japan, statues of Jizō, a Buddhist patron deity of children, memorialize stillborn babies.

Australia

In Australia, stillbirth is defined as a baby born with no signs of life that weighs more than 400 grams, or more than 20 weeks in gestation. They legally must have their birth registered.[62]

Austria

In Austria, a stillbirth is defined as a birth of a child of at least 500g weight without vital signs, e.g. blood circulation, breath or muscle movements.[63]

Canada

Beginning in 1959, "the definition of a stillbirth was revised to conform, in substance, to the definition of fetal death recommended by the World Health Organization".[64] The definition of "fetal death" promulgated by the World Health Organization in 1950 is as follows:

"Fetal death" means death prior to the complete expulsion or extraction from its mother of a product of human conception, irrespective of the duration of pregnancy and which is not an induced termination of pregnancy.[63] The death is indicated by the fact that after such expulsion or extraction, the fetus does not breathe or show any other evidence of life, such as beating of the heart, pulsation of the umbilical cord, or definite movement of voluntary muscles.[44] Heartbeats are to be distinguished from transient cardiac contractions; respirations are to be distinguished from fleeting respiratory efforts or gasps.[65]

Germany

Monument to stillborn babies in Germany

In Germany, a stillbirth is defined as the birth of a child of at least 500g weight without blood circulation or breath. Details for burial vary amongst the federal states.[66]

Republic of Ireland

At one time, this Angels' Plot was one of the few burial grounds for stillborn babies that was consecrated by the Catholic Church in Ireland.

Since 1 January 1995, stillbirths occurring in the Republic of Ireland must be registered; stillbirths that occurred before that date can also be registered but evidence is required.[67] For the purposes of civil registration, s.1 of the Stillbirths Registration Act 1994 refers to "...a child weighing at least 500 grammes, or having reached a gestational age of at least 24 weeks who shows no signs of life."

Netherlands

In the Netherlands, stillbirth is defined differently by the Central Bureau of Statistics (CBS) and the Dutch Perinatal Registry (Stichting PRN[68]). The birth and mortality numbers from the CBS include all livebirths, regardless of gestational duration, and all stillbirths from 24 weeks of gestation and onwards.[69] In the Perinatal Registry, gestational duration of both liveborn and stillborn children is available.[70] They register all liveborn and stillborn children from 22, 24 or 28 weeks of gestation and onwards (dependent on the report: fetal, neonatal or perinatal mortality).[71] Therefore, data from these institutions on (still)births can not simply be compared one-on-one.

United Kingdom

The registration of stillbirths has been required in England and Wales from 1927 and in Scotland from 1939 but is not required in Northern Ireland.[72] Sometimes a pregnancy is terminated deliberately during a late phase, for example due to congenital anomaly.[73] UK law requires these procedures to be registered as "stillbirths".[74]

England and Wales

For the purposes of the Births and Deaths Registration Act 1926 (as amended), section 12 contains the definition:

"still-born" and "still-birth" shall apply to any child which has issued forth from its mother after the twenty fourth week of pregnancy and which did not at any time after being completely expelled from its mother, breathe or show any other signs of life.

A similar definition is applied within the Births and Deaths Registration Act 1953 (as amended), contained in s.41.

The above definitions apply within those Acts thus other legislation will not necessarily be in identical terms.

s.2 of the 1953 Act requires that registration of a birth takes place within 42 days of the birth except where an inquest takes place or the child has been "found exposed" in which latter case the time limit runs from the time of finding.

Extracts from the register of stillbirths are restricted to those who have obtained consent from the Registrar General for England and Wales.[75]

Scotland

Section 56(1) of the Registration of Births, Deaths and Marriages (Scotland) Act 1965 (as amended) contains the definition:

"still-born child" means a child which has issued forth from its mother after the twenty-fourth week of pregnancy and which did not at any time after being completely expelled from its mother breathe or show any other signs of life, and the expression "still-birth" shall be construed accordingly

s.21(1) of the same Act requires that:

Except so far as otherwise provided by this section or as may be prescribed, the provisions of this Part of this Act shall, so far as applicable, apply to still-births in like manner as they apply to births of children born alive.

In the general case, s.14 of the Act requires that a birth has to be registered within 21 days of the birth or of the child being found.

Unlike the registers for births, marriages, civil partnerships and deaths, the register of still-births is not open to public access and issue of extracts requires the permission of the Registrar General for Scotland.[76]

Northern Ireland

In Northern Ireland, the Births and Deaths Registration (Northern Ireland) Order 1976,[77] as amended contains the definition:

"still-birth" means the complete expulsion or extraction from its mother after the twenty-fourth week of pregnancy of a child which did not at any time after being completely expelled or extracted breathe or show any other evidence of life.

Registration of stillbirths can be made by a relative or certain other persons involved with the stillbirth but it is not compulsory to do so.[78] Registration takes place with the District Registrar for the Registration District where the still-birth occurred or for the District in which the mother is resident.[79] A stillbirth certificate will be issued to the registrant with further copies only available to those obtaining official consent for their issue.[80] Registration may be made within three months of the still-birth.[72]

United States

In the United States, there is no standard definition of the term 'stillbirth'.[65]

In the U.S., the Born-Alive Infants Protection Act of 2002 specifies that any breathing, heartbeat, pulsating umbilical cord or confirmed voluntary muscle movement indicate live birth rather than stillbirth.[81]

The Centers for Disease Control and Prevention collects statistical information on "live births, fetal deaths, and induced termination of pregnancy" from 57 reporting areas in the United States.[82] Each reporting area has different guidelines and definitions for what is being reported; many do not use the term "stillbirth" at all.[37] The federal guidelines suggest (at page 1) that fetal death and stillbirth can be interchangeable terms. The CDC definition of "fetal death" is based on the definition promulgated by the World Health Organization in 1950 (see section above on Canada).[83] Researchers are learning more about the long term psychiatric sequelae of traumatic birth and believe the effects may be intergenerational[84]

The CDC states that, in the US, a stillbirth is typically defined as the loss of a fetus during or after the 20th week of pregnancy. Stillbirths can further be classified as early (occurring between week 20 and week 27 of pregnancy), late (occurring between week 28 and week 36 of pregnancy), and term (occurring during or after week 37 of pregnancy). In the US, approximately 21,000 babies are stillborn annually, and stillbirth affects around 1 in 175 births.[85]

The federal guidelines recommend reporting those fetal deaths whose birth weight is over 12.5 oz (350 g), or those more than 20 weeks gestation.[63] Forty-one areas use a definition very similar to the federal definition, thirteen areas use a shortened definition of fetal death, and three areas have no formal definition of fetal death. Only 11 areas specifically use the term 'stillbirth', often synonymously with late fetal death; however, they are split between whether stillbirths are "irrespective of the duration of pregnancy", or whether some age or weight constraint is applied. A movement in the U.S.[63] has changed the way that stillbirths are documented through vital records. Previously, only the deaths were reported. However, 27 states have enacted legislation that offers some variation of a birth certificate as an option for parents who choose to pay for one.[86] Parents may not claim a tax exemption for stillborn infants, even if a birth certificate is offered. To claim an exemption, the birth must be certified as live, even if the infant only lives for a very brief period.[87]

See also

  • Coffin birth
  • Perinatal death
  • Smoking and pregnancy
  • Sands (charity)

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 "Stillbirth: Overview". 23 September 2014. https://www.nichd.nih.gov/health/topics/stillbirth/Pages/default.aspx. 
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 "Stillbirth" (in en-GB). https://www.who.int/health-topics/stillbirth. 
  3. ↑ 3.0 3.1 "What are possible causes of stillbirth?". 23 September 2014. https://www.nichd.nih.gov/health/topics/stillbirth/topicinfo/Pages/causes.aspx. 
  4. ↑ 4.0 4.1 "What are the risk factors for stillbirth?". 23 September 2014. https://www.nichd.nih.gov/health/topics/stillbirth/topicinfo/Pages/risk.aspx. 
  5. ↑ 5.0 5.1 5.2 "How is stillbirth diagnosed?". 23 September 2014. https://www.nichd.nih.gov/health/topics/stillbirth/topicinfo/Pages/diagnosed.aspx. 
  6. ↑ 6.0 6.1 "How do health care providers manage stillbirth?". 23 September 2014. https://www.nichd.nih.gov/health/topics/stillbirth/topicinfo/Pages/managed.aspx. 
  7. ↑ "Stillbirth (UNICEF Data)" (in en-US). https://data.unicef.org/topic/child-survival/stillbirths/. 
  8. ↑ "What is Stillbirth?". Center of Disease Control and Prevention. https://www.cdc.gov/ncbddd/stillbirth/facts.html. 
  9. ↑ "Macerated Stillbirth". Keeling's Fetal and Neonatal Pathology. Cham: Springer International Publishing. 2022. pp. 345–368. doi:10.1007/978-3-030-84168-3_15. ISBN 978-3-030-84168-3. 
  10. ↑ 10.0 10.1 10.2 "Pregnancy loss". Best Practice & Research. Clinical Obstetrics & Gynaecology 28 (1): 169–178. January 2014. doi:10.1016/j.bpobgyn.2013.08.012. PMID 24047642. 
  11. ↑ "Progesterone for the prevention of threatened miscarriage" (in English). Obstetrics, Gynaecology and Reproductive Medicine 32 (3): 44–47. 2022-03-01. doi:10.1016/j.ogrm.2022.01.005. 
  12. ↑ Edeib, Duaa (29 November 2022). "After a Stillbirth, an Autopsy Can Provide Answers. Too Few of Them Are Being Performed.". ProPublica. https://www.propublica.org/article/stillbirths-autopsy-placenta-exams-pregnancy. 
  13. ↑ 13.0 13.1 13.2 13.3 "Stillbirths: rates, risk factors, and acceleration towards 2030". Lancet 387 (10018): 587–603. February 2016. doi:10.1016/S0140-6736(15)00837-5. PMID 26794078. 
  14. ↑ 14.0 14.1 "Ending preventable stillbirths An Executive Summary for The Lancet's Series". The Lancet. Jan 2016. http://www.thelancet.com/pb/assets/raw/Lancet/stories/series/stillbirths2016-exec-summ.pdf. 
  15. ↑ "Stillbirth: Other FAQs". 23 September 2014. https://www.nichd.nih.gov/health/topics/stillbirth/topicinfo/Pages/questions.aspx. 
  16. ↑ 16.0 16.1 16.2 "Stillbirths" (in en-US). https://data.unicef.org/topic/child-survival/stillbirths/. 
  17. ↑ "Stillbirths and stillbirth rates" (in en-US). https://data.unicef.org/topic/child-survival/stillbirths/. 
  18. ↑ 18.0 18.1 "Stillbirths: rates, risk factors, and acceleration towards 2030". Lancet 387 (10018): 587–603. February 2016. doi:10.1016/S0140-6736(15)00837-5. PMID 26794078. 
  19. ↑ "Classification systems for causes of stillbirth and neonatal death, 2009–2014: an assessment of alignment with characteristics for an effective global system". BMC Pregnancy and Childbirth 16: 269. September 2016. doi:10.1186/s12884-016-1040-7. PMID 27634615. 
  20. ↑ "Umbilical cord accidents: human studies". Seminars in Perinatology 26 (1): 79–82. February 2002. doi:10.1053/sper.2002.29860. PMID 11876571. 
  21. ↑ 21.0 21.1 21.2 Cacciatore J (2007-01-01). A phenomenological exploration of stillbirth and the effects of ritualization on maternal anxiety and depression (Thesis). University of Nebraska - Lincoln. Archived from the original on 2016-10-18.
  22. ↑ 22.0 22.1 "Novel strategies to prevent stillbirth". Seminars in Fetal & Neonatal Medicine 22 (3): 146–152. June 2017. doi:10.1016/j.siny.2017.01.005. PMID 28162972. https://unisa.alma.exlibrisgroup.com/view/delivery/61USOUTHAUS_INST/12146787690001831. 
  23. ↑ "Tobacco, Alcohol, and Drugs During Pregnancy" (in en-US). 2018-03-12. https://familydoctor.org/tobacco-alcohol-drugs-pregnancy/. 
  24. ↑ "Celiac disease and obstetric complications: a systematic review and metaanalysis". American Journal of Obstetrics and Gynecology 214 (2): 225–234. February 2016. doi:10.1016/j.ajog.2015.09.080. PMID 26432464. 
  25. ↑ "Female genital mutilation and obstetric outcome: WHO collaborative prospective study in six African countries". Lancet (London) 367 (9525): 1835–1841. June 2006. doi:10.1016/S0140-6736(06)68805-3. PMID 16753486. https://www.who.int/reproductivehealth/publications/fgm/fgm-obstetric-study-en.pdf. 
  26. ↑ "What Is Umbilical Cord Prolapse?" (in en). 5 March 2021. https://www.webmd.com/parenting/what-is-umbilical-cord-prolapse. 
  27. ↑ "An Individual Participant Data Meta-analysis of Maternal Going-to-Sleep Position, Interactions with Fetal Vulnerability, and the Risk of Late Stillbirth". eClinicalMedicine 10: 49–57. April 2019. doi:10.1016/j.eclinm.2019.03.014. PMID 31193832. 
  28. ↑ "Risk of recurrent stillbirth: systematic review and meta-analysis". BMJ 350: h3080. June 2015. doi:10.1136/bmj.h3080. PMID 26109551. 
  29. ↑ "What is Stillbirth?" (in en-us). 2019-05-09. https://www.cdc.gov/ncbddd/stillbirth/facts.html. 
  30. ↑ "Excessive fetal movements are a sign of fetal compromise which merits further examination". Medical Hypotheses 111: 19–23. February 2018. doi:10.1016/j.mehy.2017.12.024. PMID 29406989. http://eprints.whiterose.ac.uk/125347/8/YMEHY_2017_982_Original_V0.pdf. 
  31. ↑ "Fetal Movements in Pregnancy" (in en). 2015-03-12. https://www.news-medical.net/health/Fetal-Movements-in-Pregnancy.aspx. 
  32. ↑ "Fetal development: Month-By-Month Stages of Pregnancy". https://my.clevelandclinic.org/health/articles/7247-fetal-development-stages-of-growth. 
  33. ↑ "Reducing stillbirths: screening and monitoring during pregnancy and labour". BMC Pregnancy and Childbirth 9 (Suppl 1): S5. May 2009. doi:10.1186/1471-2393-9-S1-S5. PMID 19426468. 
  34. ↑ "Non-reassuring fetal status: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data". Vaccine 34 (49): 6084–6092. December 2016. doi:10.1016/j.vaccine.2016.03.043. PMID 27461459. 
  35. ↑ "Fetal environment". The Indian Journal of Radiology & Imaging 18 (4): 326–344. November 2008. doi:10.4103/0971-3026.43848. PMID 19774194. 
  36. ↑ "Predicting stillbirth in a low resource setting". BMC Pregnancy and Childbirth 16 (1): 274. September 2016. doi:10.1186/s12884-016-1061-2. PMID 27649795. 
  37. ↑ 37.0 37.1 37.2 37.3 37.4 "Stillbirth: Definition, Causes & Prevention". https://my.clevelandclinic.org/health/diseases/9685-stillbirth. 
  38. ↑ "Terms in reproductive and perinatal epidemiology: 2. Perinatal terms". Journal of Epidemiology and Community Health 59 (12): 1019–1021. December 2005. doi:10.1136/jech.2004.023465. PMID 16286486. "There is probably no health outcome with a greater number of conflicting, authoritative, legally mandated definitions. The basic WHO definition of fetal death is the intrauterine death of any conceptus at any time during pregnancy. However, for practical purposes, legal definitions usually require recorded fetal deaths to attain some gestational age (16, 20, 22, 24, or 28 weeks) or birth weight (350, 400, 500, or 1000 g). In the US states, there are eight different definitions by combinations of gestational age and weight, and at least as many in Europe.". 
  39. ↑ "halden fgr experiments: Topics by Science.gov". https://www.science.gov/topicpages/h/halden+fgr+experiments. 
  40. ↑ "Braxton Hicks Contractions". StatPearls. Treasure Island (FL): StatPearls Publishing. 2022. http://www.ncbi.nlm.nih.gov/books/NBK470546/. Retrieved 2022-04-27. 
  41. ↑ "Umbilical Cord Complications: Overview, Cord Length, Single Umbilical Artery". Medscape. 2021-10-16. https://emedicine.medscape.com/article/262470-overview. 
  42. ↑ "Reducing stillbirths: prevention and management of medical disorders and infections during pregnancy". BMC Pregnancy and Childbirth 9 (Suppl 1): S4. May 2009. doi:10.1186/1471-2393-9-S1-S4. PMID 19426467. 
  43. ↑ WebMD (December 14, 2011). "Studies identify stillbirth risk factors, causes". CBS News. http://www.cbsnews.com/8301-500368_162-57342588/studies-identify-stillbirth-risk-factors-causes/. 
  44. ↑ 44.0 44.1 "Evaluation of Fetal Death: Definition of Fetal Death, Frequency of Fetal Death, Diagnosis of Fetal Death". Medscape. 2022-02-15. https://emedicine.medscape.com/article/259165-overview. 
  45. ↑ "Vaginal Bleeding During Late Pregnancy - Women's Health Issues" (in en). June 2021. https://www.msdmanuals.com/home/women-s-health-issues/symptoms-during-pregnancy/vaginal-bleeding-during-late-pregnancy. 
  46. ↑ "Vaginal Birth: Is It Possible After a C-Section?" (in en). https://www.webmd.com/baby/vaginal-birth-after-c-section. 
  47. ↑ "Communication skills in Obstetrics: what can we learn from bereaved parents?". Irish Medical Journal 110 (2): 512. February 2017. PMID 28657257. http://imj.ie/communication-skills-in-obstetrics-what-can-we-learn-from-bereaved-parents/. 
  48. ↑ "Cooling 'cuddle cot' allows extra time with stillborn babies". The Irish Times (Dublin, Ireland). 9 May 2016. https://www.irishtimes.com/life-and-style/health-family/parenting/cooling-cuddle-cot-allows-extra-time-with-stillborn-babies-1.2634818. 
  49. ↑ "Preparing for labour and birth with a stillborn baby". Tommy's. London. https://www.tommys.org/baby-loss-support/stillbirth-information-and-support/giving-birth-stillborn-baby. 
  50. ↑ "Placental, pregnancy conditions account for most stillbirths". NIH News. U.S. Department of Health and Human Services.. 13 December 2011. http://www.nih.gov/news/health/dec2011/nichd-13.htm. 
  51. ↑ "Department of Neonatal Medicine Protocol Book: Royal Prince Alfred Hospital". http://www.sswahs.nsw.gov.au/RPA/neonatal/html/Newprot/stillbirths.html. 
  52. ↑ "Statistical bulletin: Live Births, Stillbirths and Infant Deaths, Babies Born in 2009 in England and Wales". Office for National Statistics. 21 June 2012. http://www.ons.gov.uk/ons/rel/vsob1/birth-cohort-tables--england-and-wales/2009/stb-bct-2009.html. 
  53. ↑ "Release: Characteristics of Birth 1, England and Wales, 2011". Office for National Statistics. 31 October 2012. http://www.ons.gov.uk/ons/rel/vsob1/characteristics-of-birth-1--england-and-wales/2011/index.html. "Stillbirths per 1,000 live births have increased from 5.1 in 2010 to 5.2 in 2011" 
  54. ↑ "Maternal and fetal risk factors for stillbirth in Northern Tanzania: A registry-based retrospective cohort study". PLOS ONE 12 (8): e0182250. 2017-08-15. doi:10.1371/journal.pone.0182250. PMID 28813528. Bibcode: 2017PLoSO..1282250C. 
  55. ↑ "Meeting abstracts from the International Stillbirth Alliance Conference 2017". BMC Pregnancy and Childbirth 17 (1): 1–47. 2017-09-01. doi:10.1186/s12884-017-1457-7. ISSN 1471-2393. 
  56. ↑ "How common is stillbirth?". 23 September 2014. https://www.nichd.nih.gov/health/topics/stillbirth/topicinfo/Pages/how-common.aspx. 
  57. ↑ "Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet 388 (10053): 1725–1774. October 2016. doi:10.1016/S0140-6736(16)31575-6. PMID 27733285. 
  58. ↑ "Stillbirths: economic and psychosocial consequences". Lancet 387 (10018): 604–616. February 2016. doi:10.1016/S0140-6736(15)00836-3. PMID 26794073. https://philarchive.org/rec/HEASEA. 
  59. ↑ "Parental Reactions to Stillbirth". The British Journal of Social Work 10 (1): 55–69. 1980. doi:10.1093/oxfordjournals.bjsw.a054495.  Understanding reproductive loss: perspectives on life, death and fertility. Ashgate Publishing Ltd.. 2012. ISBN 978-1-4094-2810-7. https://books.google.com/books?id=kR2ZbeGWXIwC. 
  60. ↑ "From grief, guilt pain and stigma to hope and pride - a systematic review and meta-analysis of mixed-method research of the psychosocial impact of stillbirth". BMC Pregnancy and Childbirth 16 (1): 9. January 2016. doi:10.1186/s12884-016-0800-8. PMID 26785915. 
  61. ↑ "The impact of pregnancy loss on men's health and wellbeing: a systematic review". BMC Pregnancy and Childbirth 17 (1): 380. November 2017. doi:10.1186/s12884-017-1560-9. PMID 29141591. 
  62. ↑ "Chorioamnionitis and fetal response in stillbirth". American Journal of Obstetrics and Gynecology 196 (3): 229.e1–229.e4. March 2007. doi:10.1016/j.ajog.2006.10.900. PMID 17346531. "Stillbirth is defined within Australia as fetal death (no signs of life), whether antepartum or intrapartum, at ≥20 weeks of gestation or ≥400 g birthweight, if gestational age is unknown.". 
  63. ↑ 63.0 63.1 63.2 63.3 "Stillbirth: Case definition and guidelines for data collection, analysis, and presentation of maternal immunization safety data". Vaccine 34 (49): 6057–6068. December 2016. doi:10.1016/j.vaccine.2016.03.044. PMID 27431422. 
  64. ↑ "History, Vital Statistics – Stillbirth Database (Survey number 3234)". Statistics Canada (Canada's National Statistical Agency). http://www.statcan.ca/english/sdds/document/3234_D2_T9_V1_E.pdf. 
  65. ↑ 65.0 65.1 Centers for Disease Control and Prevention. State Definitions and Reporting Requirements (1997 Revision ed.). National Center for Health Statistics. https://www.cdc.gov/nchs/data/misc/itop97.pdf. 
  66. ↑ "Gesetze". Initiative-regenbogen.de. http://www.initiative-regenbogen.de/gesetze.htm. 
  67. ↑ "Registering a stillbirth". citizensinformation.ie. http://www.citizensinformation.ie/categories/birth-family-relationships/miscarriage-and-stillbirth/registering_stillbirth. 
  68. ↑ "Ethnic differences in stillbirth and early neonatal mortality in The Netherlands". Journal of Epidemiology and Community Health 65 (8): 696–701. August 2011. doi:10.1136/jech.2009.095406. PMID 20719806. 
  69. ↑ "Determinants of stillbirths in katsina, Nigeria: a hospital-based study". Pediatric Reports 7 (1): 5615. February 2015. doi:10.4081/pr.2015.5615. PMID 25918622. 
  70. ↑ "The Perinatal Database of the Netherlands". European Journal of Obstetrics, Gynecology, and Reproductive Biology 94 (1): 125–138. January 2001. doi:10.1016/s0301-2115(00)00295-5. PMID 11134838. 
  71. ↑ "Perinatal epidemiology.". International Encyclopedia of Public Health. Elsevier. 208. pp. 45–53. doi:10.1016/B978-012373960-5.00199-4. ISBN 978-0-12-373960-5. 
  72. ↑ 72.0 72.1 "Registering a still-birth". www.nidirect.gov.uk. Belfast, Northern Ireland. http://www.nidirect.gov.uk/index/information-and-services/government-citizens-and-rights/births-and-registration/registering-a-still-birth.htm. 
  73. ↑ "Cell-Free DNA-Based Noninvasive Prenatal Testing and Society.". Noninvasive Prenatal Testing (NIPT). Academic Press. January 2018. pp. 235–249. doi:10.1016/B978-0-12-814189-2.00014-1. ISBN 9780128141892. 
  74. ↑ "The contribution of late termination of pregnancy to stillbirth rates in Northern England, 1994-2005". BJOG 115 (5): 664–666. April 2008. doi:10.1111/j.1471-0528.2008.01668.x. PMID 18333949. 
  75. ↑ "Stillbirth registration and perceptions of infant death, 1900-60: the Scottish case in national context". The Economic History Review 62 (3): 629–654. August 2009. doi:10.1111/j.1468-0289.2009.00478.x. PMID 20098665. 
  76. ↑ "National Records of Scotland" (in English). 2013-05-31. https://www.nrscotland.gov.uk/registration/about-registration-in-scotland. 
  77. ↑ "Births and Deaths Registration (Northern Ireland) Order 1976". Legislation.gov.uk. http://www.legislation.gov.uk/nisi/1976/1041. 
  78. ↑ "Stillbirth" (in en). https://www.who.int/health-topics/stillbirth. 
  79. ↑ "What is birth registration and why does it matter?" (in en). https://www.unicef.org/stories/what-birth-registration-and-why-does-it-matter. 
  80. ↑ "Registering a stillbirth" (in en). 2015-10-20. https://www.nidirect.gov.uk/articles/registering-stillbirth. 
  81. ↑ "House Report 107-186 – Born-Alive Infants Protection Act of 2001". gpo.gov. http://frwebgate.access.gpo.gov/cgi-bin/getdoc.cgi?dbname=107_cong_reports&docid=f:hr186.107. 
  82. ↑ State Definitions and Reporting Requirements (1997 Revision ed.). National Center for Health Statistics. http://www.cdc.gov/nchs/data/misc/itop97.pdf. 
  83. ↑ National Research Council (US) Committee on National Statistics (2009) (in en). The U.S. Vital Statistics System: A National Perspective. National Academies Press (US). https://www.ncbi.nlm.nih.gov/books/NBK219884/. 
  84. ↑ "The unique experiences of women and their families after the death of a baby". Social Work in Health Care 49 (2): 134–148. 2010. doi:10.1080/00981380903158078. PMID 20175019. 
  85. ↑ "What is Stillbirth?". 29 September 2022. https://www.cdc.gov/ncbddd/stillbirth/facts.html. 
  86. ↑ "Convention on the Rights of the Child text" (in en). https://www.unicef.org/child-rights-convention/convention-text. 
  87. ↑ "Coma and cerebral imaging". SpringerPlus 4: 180. 2015-04-16. doi:10.1186/s40064-015-0869-y. PMID 25984436. 

External links

Classification
External resources
  • G. J. Barker-Benfield, "Stillbirth and Sensibility The Case of Abigail and John Adams", Early American Studies, An Interdisciplinary Journal, Spring 2012, Vol. 10 Issue 1, pp 2–29.
  • Lancet series on stillbirth 2016



Retrieved from "https://handwiki.org/wiki/index.php?title=Medicine:Stillbirth&oldid=3275056"