Medicine:List of reference ranges for cerebrospinal fluid

From HandWiki

Following is a list of reference ranges for cerebrospinal fluid:

Ions and metals

Reference ranges for ions and metals in CSF [1]
Substance Lower limit Upper limit Unit Corresponds to % of that in plasma[clarification needed]
Osmolality 280[1] 300[1] mmol/L
Sodium 135[1] 150[1] mmol/L
Potassium 2.6[1] 3.0[1] mmol/L
Chloride 115[1] 130[1] mmol/L >100%[1]
Calcium 1.00[1] 1.40[1] mmol/L ~50%[1]
Magnesium 1.2[1] 1.5[1] mmol/L >100%[1]
Iron 0.2[1] 0.4[1] µmol/L

Other molecules

Reference ranges for other molecules in CSF
Substance Lower limit Upper limit Unit Corresponds to % of that in plasma
Glucose 50[2] 80[2] mg/dL ~60%[1]
2.2,[3] 2.8[1] 3.9,[3] 4.4[1] mmol/L
Protein 15[1][2] 40,[4] 45[1][2] mg/dL ~1%[1]
Albumin 7.8[5] 40[5] mg/dL 0[6] - 0.7%[6]
- corresponding to an albumin (CSF/serum) quotient of 0 to 7x10−3
Lactate 1.1[1] 2.4[1] mmol/L
Creatinine 50[1] 110[1] µmol/L
Phosphorus 0.4[1] 0.6[1] µmol/L
Urea 3.0[1] 6.5[1] mmol/L
Carbon dioxide 20[1] 25[1] mmol/L

Other CSF constituents

Reference ranges for other CSF constituents
Substance Lower limit Upper limit Unit Corresponds to % of that in blood plasma
RBCs n/a[2] 0[2] / negative cells/µL or
cells/mm3
WBCs 0[2] 3[2] cells/µL
cells/mm3
pH 7.28[1] 7.32[1] (-log M)
PCO2 44[1] 50[1] mmHg
5.9[7] 6.7[7] kPa
PO2 40[1] 44[1] mmHg
5.3[7] 5.9[7] kPa

References

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 1.21 1.22 1.23 1.24 1.25 1.26 1.27 1.28 1.29 1.30 1.31 1.32 1.33 1.34 1.35 1.36 1.37 1.38 1.39 PATHOLOGY 425 CEREBROSPINAL FLUID [CSF] at the Department of Pathology and Laboratory Medicine at the University of British Columbia. By Dr. G.P. Bondy. Retrieved November 2011 [|permanent dead link|dead link}}]
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Normal Reference Range Table from The University of Texas Southwestern Medical Center at Dallas. Used in Interactive Case Study Companion to Pathologic basis of disease.
  3. 3.0 3.1 Department of Chemical Pathology at the Chinese University of Hong Kong , in turn citing: Roberts WL et al. Reference Information for the Clinical Laboratory. In Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 4th edn. Burtis CA, Ashwood ER and Bruns DE eds. Elsevier Saunders 2006; 2251 - 2318
  4. Felgenhauer K (1974). "Protein size and CSF composition". Klin. Wochenschr. 52 (24): 1158–64. doi:10.1007/BF01466734. PMID 4456012. 
  5. 5.0 5.1 Lab Manual for SFGH > PROTEIN, CSF - IgG INDEX at The University of California, San Francisco. Last updated 10/4/2010.
  6. 6.0 6.1 Standardization of procedures and methods in neuroimmunology from the Italian Association of Neuroimmunology. Retrieved January, 2012
  7. 7.0 7.1 7.2 7.3 Derived from mmHg values using 0.133322 kPa/mmHg