Medicine:Pooled analysis

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Short description: Statistical technique used to combine multiple study results

A pooled analysis is a statistical technique for combining the results of multiple epidemiological studies. It is one of three types of literature reviews frequently used in epidemiology, along with meta-analysis and traditional narrative reviews. Pooled analyses may be either retrospective or prospective.[1] It is often used when the results of individual studies do not allow for a firm conclusion to be drawn.[2] Unlike meta-analyses, pooled analyses can only be conducted if the included studies used the same study design and statistical models, and if their respective populations were homogeneous. If individual-level data from the included studies is available, the result of a pooled analysis can be considered more reliable.[3]

References

  1. Friedenreich, Christine M (2002-02-01). "Commentary: Improving pooled analyses in epidemiology" (in en). International Journal of Epidemiology 31 (1): 86–87. doi:10.1093/ije/31.1.86. ISSN 0300-5771. PMID 11914300. 
  2. Taioli, Emanuela; Bonassi, Stefano (2003-01-01). "Pooled analysis of epidemiological studies involving biological markers" (in en). International Journal of Hygiene and Environmental Health 206 (2): 109–115. doi:10.1078/1438-4639-00198. ISSN 1438-4639. PMID 12708232. 
  3. Blettner, M (1999-02-01). "Traditional reviews, meta-analyses and pooled analyses in epidemiology" (in en). International Journal of Epidemiology 28 (1): 1–9. doi:10.1093/ije/28.1.1. ISSN 0300-5771. PMID 10195657.