Medicine:Protein nitrogen unit

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Short description: Measurement unit

The protein nitrogen unit (PNU) measures the potency of the compounds used in allergy skin tests, and is equivalent to 0.01 microgram (µg) of phosphotungstic acid-precipitable protein nitrogen.[1] Potency measurements depend on the measurement technique, so that results from different manufacturers cannot be reliably compared: as a result, PNUs are being replaced by bioequivalent allergy units (BAU), which are measured by skin testing using reference preparations of standard potency.[2]

Notes

  1. May, JC et al. (November 1981). "Protein nitrogen unit precipitation procedure for allergenic extracts: collaborative study". Journal of the Association of Official Analytical Chemists 64 (6): 1435–8. doi:10.1093/jaoac/64.6.1435. PMID 7309663. 
  2. Ross, Rowlett (2002). "P". How Many? A Dictionary of Units of Measurement. University of North Carolina at Chapel Hill. http://www.unc.edu/~rowlett/units/dictP.html. Retrieved 2009-02-05.