Medicine:Young's syndrome
| Young's syndrome | |
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| Other names | Azoospermia sinopulmonary infections |
Young's syndrome, also known as azoospermia sinopulmonary infections, sinusitis-infertility syndrome and Barry-Perkins-Young syndrome, is a rare condition that encompasses a combination of syndromes such as bronchiectasis, rhinosinusitis and reduced male fertility.[1][2][3] In individuals with this syndrome the functioning of the lungs is usually normal but the mucus is abnormally viscous. The reduced fertility (obstructive azoospermia) is due to functional obstruction of sperm transport down the genital tract at the epididymis, where the sperm is found in viscous, lipid-rich fluid.[3][4] The syndrome was named after Donald Young,[5] the urologist who first made observations of the clinical signs of the syndrome in 1972.[6] Possible causes include genetics, and exposure to mercury during childhood, but the cause is unknown.[2]
Causes
Young's syndrome is caused by helminthiasis where specific parasites are attacking the reproductive organs.[7]
See also
References
- ↑ "Young's syndrome. Obstructive azoospermia and chronic sinopulmonary infections". N. Engl. J. Med. 310 (1): 3–9. January 1984. doi:10.1056/NEJM198401053100102. PMID 6689737.
- ↑ 2.0 2.1 Young syndrome at NIH's Office of Rare Diseases
- ↑ 3.0 3.1 Young's syndrome - General Practice Notebook
- ↑ Definition: Young syndrome from Online Medical Dictionary
- ↑ Young, M (January 2003). "Obituary of Donald Herron Young". BMJ 326 (7382): 226. doi:10.1136/bmj.326.7382.226/g.
- ↑ Online Mendelian Inheritance in Man (OMIM) Young syndrome -279000
- ↑ Blackwell, Aaron D.; Tamayo, Marilyne A.; Beheim, Bret; Trumble, Benjamin C.; Stieglitz, Jonathan; Hooper, Paul L.; Martin, Melanie; Kaplan, Hillard et al. (2015). "Helminth infection, fecundity, and age of first pregnancy in women". Science 350 (6263): 970–972. doi:10.1126/science.aac7902. PMID 26586763.
- "Young's syndrome. An association between male sterility and bronchiectasis". West. J. Med. 144 (6): 744–6. June 1986. PMID 3727536.
External links
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