Organization:BioImage Archive

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Short description: Research data repository

The BioImage Archive (BIA) is a research data repository hosting publicly accessible bioimaging datasets. It is hosted by the European Bioinformatics Institute, in the United Kingdom.[1][2] It was first announced on 2 July 2019. [3]

Its creation was proposed in 2018 to cater for the lack of a central public repository for microscopy images in the biosciences.[4] In 2019, it was created based on the BioStudies database and extended the EMBL-EBI resources for imaging, which at the time included only EMPIAR (the Electron Microscopy Public Image Archive).[2][5] BIA was also meant as a bridge between EMPIAR and the Image Data Resource, a public bioimaging database maintained by the Open Microscopy Environment consortium.[2][6] In 2026, BioImage Archive entered the list of ELIXIR Core Data Resources.[7][8]

As of 2026, BIA holds over 2,500 datasets.[9] Datasets cover a wide range of subjects and are identified by alphanumeric identifiers of the format "S-BIAD0000". For example, a study about development of the Japanese eel is deposited under the identifier S-BIAD3325.[10] Deposition on BioImage Archive is considered as a good practice for FAIR data in bioimaging.[11][12][13]

BioImage Archive provides application program interfaces usable by the general public and other open-source software utilities.[14]

See also

References

  1. ↑ Hartley, Matthew; Kleywegt, Gerard J.; Patwardhan, Ardan; Sarkans, Ugis; Swedlow, Jason R.; Brazma, Alvis (2022-06-15). "The BioImage Archive – Building a Home for Life-Sciences Microscopy Data". Journal of Molecular Biology. Computation Resources for Molecular Biology 434 (11). doi:10.1016/j.jmb.2022.167505. ISSN 0022-2836. PMID 35189131. https://www.sciencedirect.com/science/article/pii/S0022283622000791. 
  2. ↑ 2.0 2.1 2.2 Hartley, Matthew; Kleywegt, Gerard J.; Patwardhan, Ardan; Sarkans, Ugis; Swedlow, Jason R.; Brazma, Alvis (2022-02-11), "The BioImage Archive - building a home for life-sciences microscopy data" (in en), Journal of Molecular Biology (bioRxiv) 434 (11), doi:10.1101/2021.12.17.473169, PMID 35189131, https://www.biorxiv.org/content/10.1101/2021.12.17.473169v2, retrieved 2026-08-25 
  3. ↑ Reither, Sabine (2019-07-02). "The Bioimage Archive has been announced today by EMBL-EBI" (in en-US). https://gerbi-gmb.de/2019/07/02/the-bioimage-archive-has-been-announced-today-by-embl-ebi/. 
  4. ↑ Ellenberg, Jan; Swedlow, Jason R.; Barlow, Mary; Cook, Charles E.; Sarkans, Ugis; Patwardhan, Ardan; Brazma, Alvis; Birney, Ewan (November 2018). "A call for public archives for biological image data" (in en). Nature Methods 15 (11): 849–854. doi:10.1038/s41592-018-0195-8. ISSN 1548-7105. PMID 30377375. 
  5. ↑ Iudin, Andrii; Korir, Paul K; Somasundharam, Sriram; Weyand, Simone; Cattavitello, Cesare; Fonseca, Neli; Salih, Osman; Kleywegt, Gerard J et al. (2023-01-06). "EMPIAR: the Electron Microscopy Public Image Archive". Nucleic Acids Research 51 (D1): D1503–D1511. doi:10.1093/nar/gkac1062. ISSN 0305-1048. PMID 36440762. PMC 9825465. https://doi.org/10.1093/nar/gkac1062. 
  6. ↑ Williams, Eleanor; Moore, Josh; Li, Simon W.; Rustici, Gabriella; Tarkowska, Aleksandra; Chessel, Anatole; Leo, Simone; Antal, Bálint et al. (August 2017). "Image Data Resource: a bioimage data integration and publication platform" (in en). Nature Methods 14 (8): 775–781. doi:10.1038/nmeth.4326. ISSN 1548-7105. PMID 28775673. 
  7. ↑ "ELIXIR Core Data Resources | ELIXIR" (in en). https://elixir-europe.org/platforms/data/core-data-resources. 
  8. ↑ "BioImage Archive receives new Core Data Resource and Deposition Database status by ELIXIR" (in en-GB). 2026-01-13. https://www.eurobioimaging.eu/news/bioimage-archive-receives-new-core-data-resource-and-deposition-database-status-by-elixir/. 
  9. ↑ "BioImage Archive | re3data.org". https://www.re3data.org/repository/r3d100013949. 
  10. ↑ "S-BIAD3325: Heterochrony of axis segmentation underlies extreme morphogenesis in the Japanese eel". https://beta.bioimagearchive.org/bioimage-archive/study/S-BIAD3325. 
  11. ↑ "BioImage Archive | FAIRsharing" (in en). 2018. doi:10.25504/FAIRsharing.x38D2k. https://fairsharing.org/10.25504/FAIRsharing.x38D2k. 
  12. ↑ Galinova, Vera; Seifi, Mehdi; Serrano Solano, Beatriz; Lidayová, Kristína; Dalle Nogare, Damian; Corbat, Agustín Andrés; Talks, Joshua; Giacomello, Edoardo et al. (2026-07-22) (in en), AI4Life Open Calls and Public Challenges: why, how, and what we have learned, doi:10.64898/2026.07.21.739486, http://biorxiv.org/lookup/doi/10.64898/2026.07.21.739486, retrieved 2026-08-25 
  13. ↑ Ambroset, Mélodie; Valades-Cruz, Cesar Augusto; Tonfack, Libert Brice; D'Antuono, Rocco; Fuster-Barceló, Caterina (2026). "Assessing the reproducibility of a bioimage analysis workflow characterising tissue flow in Drosophila" (in en). Journal of Microscopy n/a (n/a). doi:10.1111/jmi.70125. ISSN 1365-2818. PMID 42312811. https://onlinelibrary.wiley.com/doi/abs/10.1111/jmi.70125. 
  14. ↑ Russell, Craig T; Burel, Jean-Marie; Athar, Awais; Li, Simon; Sarkans, Ugis; Swedlow, Jason; Brazma, Alvis; Hartley, Matthew et al. (2025-08-01). "bia-binder: a web-native cloud compute service for the bioimage analysis community". Bioinformatics 41 (8). doi:10.1093/bioinformatics/btaf412. ISSN 1367-4811. PMID 40692175. PMC 12342736. https://doi.org/10.1093/bioinformatics/btaf412. 



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