Organization:Biomedical Research Center

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Biomedical Research Center
Biomedical Research Center
مركز البحوث الحيوية الطبية
BRC logo-01.png
AbbreviationBRC
Formation2014
HeadquartersQatar University
Location
  • Qatar
  • Doha
Region
Middle East
ServicesResearch and Education
FieldsBiomedical science
Official language
Arabic and English
Websitehttp://www.qu.edu.qa/research/brc

The Biomedical Research Center (BRC) is a research center at Qatar University focusing on biomedical research. BRC was founded in 2014, and partners with the Ministry of Public Health (Qatar), and Hamad Medical Corporation (HMC).[1][2][3]

History

The incidence of genetic disorders in Qatar is high,[4] with the top three causes of death in the country cancer, heart diseases and diabetes.[5][6] The government saw the creation of BRC as a strategy for proactively preventing diseases to foster public health.[7][8]

BRC labs received the ISO/IEC - 17025 accreditation from the American Association for Laboratory Accreditation (A2LA).[9] The centre's research activities focus on infectious diseases (virology and microbiology), metabolic disorders, and biomedical omics.[10]

Research

photo of Qatar's dugongs
Qatar's dugongs

Since its inauguration in 2014, BRC researchers have published research papers with more than 530 publications.[11][12]

The centre's research projects include:

Zebrafish Research Model

BRC Introduced the use of zebrafish as an animal model in biomedical research at Qatar University
BRC Introduced the use of zebrafish as an animal model in biomedical research at Qatar University

BRC Introduced the use of zebrafish as an animal model in biomedical research[36][37][32][38][39][40] and established a facility for it in 2015.[41][42][43] The facility is used as a research unit to study many genetic diseases.[32] The Ministry of Public Health articulated an institutional research policy (IRP) on the use of zebrafish in research,[44] which Qatar University backed.

Facilities

Biosafety level 3 (BSL3) lab at BRC, Qatar University

The BRC facilities include:[41]

See also

References

  1. ↑ "BRC AND SCH SIGN COLLABORATIVE AGREEMENT". 2015-11-05. http://www.qu.edu.qa/newsroom/BRC/BRC-and-SCH-sign-collaborative-agreement. 
  2. ↑ "Biomedical Research Center | Qatar University". 2023. http://www.qu.edu.qa/research/brc. 
  3. ↑ "Qatar puts the pursuit of knowledge front and centre" (in en). 2023. https://www.nature.com/articles/d42473-018-00045-9. 
  4. ↑ "Research | Qatar Genome Programme". 2023. https://www.qatargenome.org.qa/research. 
  5. ↑ "Qatar" (in en). 2015-09-09. https://www.healthdata.org/qatar. 
  6. ↑ "Health and Biomedical Sciences". 2020-10-19. http://www.qu.edu.qa/research/research-priorities/health-and-biomedical-sciences. 
  7. ↑ "Qatar National Vision 2030 | General Secretariat For Development Planning". July 2008. https://www.gco.gov.qa/wp-content/uploads/2016/09/GCO-QNV-English.pdf. 
  8. ↑ "Research Pillars and Priorities | Qatar University". 2020-10-19. http://www.qu.edu.qa/research/research-priorities. 
  9. ↑ "QU BIOMEDICAL RESEARCH CENTER AND LABORATORY ANIMAL RESEARCH CENTER AWARDED ISO IEC - 17025 ACCREDITATION". 2018-07-01. http://www.qu.edu.qa/newsroom/LARC/QU-Biomedical-Research-Center-and-Laboratory-Animal-Research-Center-awarded-ISO-IEC-%E2%80%93-17025-accreditation. 
  10. ↑ "Divisions and Researches | Qatar University". http://www.qu.edu.qa/research/brc/about/divisions-and-researches. 
  11. ↑ "BRC Publications". 2022-02-24. http://www.qu.edu.qa/research/brc/about/publications. 
  12. ↑ "Qatar University Institutional Repository | Biomedical Research Center". 2023. https://qspace.qu.edu.qa/handle/10576/62. 
  13. ↑ "Pseudomonas aeruginosa: arsenal of resistance mechanisms, decades of changing resistance profiles, and future antimicrobial therapies". Future Microbiology 10 (10): 1683–1706. 2015-10-01. doi:10.2217/fmb.15.48. PMID 26439366. 
  14. ↑ "Microbiome engineering to combat antimicrobial resistance and upsurge productivity of food animals: a systematic review.". Animal Production Science 63 (2): 101–112. September 2022. doi:10.1071/AN22233. 
  15. ↑ "Prevalence of antibiotic resistant Escherichia coli isolates from fecal samples of food handlers in Qatar". Antimicrobial Resistance and Infection Control 7: 78. 2018. doi:10.1186/s13756-018-0369-2. PMID 29983931. 
  16. ↑ "Retail Chicken Carcasses as a Reservoir of Multidrug-Resistant Salmonella". Microbial Drug Resistance (Larchmont, N.Y.) 28 (7): 824–831. July 2022. doi:10.1089/mdr.2021.0414. PMID 35675669. 
  17. ↑ 17.0 17.1 "Qatar University's Biomedical Research Center conducting research on COVID-19" (in en). The Peninsula Newspaper. 2020-03-29. https://thepeninsulaqatar.com/article/29/03/2020/Qatar-University%E2%80%99s-Biomedical-Research-Center-conducting-research-on-COVID-19. 
  18. ↑ "Metabolic signature of obesity-associated insulin resistance and type 2 diabetes". Journal of Translational Medicine 17 (1): 348. October 2019. doi:10.1186/s12967-019-2096-8. PMID 31640727. 
  19. ↑ "WCM-Q research probes causal link between obesity and diabetes" (in en-US). December 2019. https://qatar-weill.cornell.edu/media-and-news/news/story/wcm-q-research-probes-causal-link-between-obesity-and-diabetes. 
  20. ↑ "Evaluation of candidate vaccine approaches for MERS-CoV". Nature Communications 6 (1): 7712. July 2015. doi:10.1038/ncomms8712. PMID 26218507. Bibcode: 2015NatCo...6.7712W. 
  21. ↑ "mRNA-1273 COVID-19 vaccine effectiveness against the B.1.1.7 and B.1.351 variants and severe COVID-19 disease in Qatar". Nature Medicine 27 (9): 1614–1621. September 2021. doi:10.1038/s41591-021-01446-y. PMID 34244681. 
  22. ↑ "BNT162b2 and mRNA-1273 COVID-19 vaccine effectiveness against the SARS-CoV-2 Delta variant in Qatar". Nature Medicine 27 (12): 2136–2143. December 2021. doi:10.1038/s41591-021-01583-4. PMID 34728831. 
  23. ↑ "Challenges in Laboratory Diagnosis of the Novel Coronavirus SARS-CoV-2". Viruses 12 (6): 582. May 2020. doi:10.3390/v12060582. PMID 32466458. 
  24. ↑ "Waning of BNT162b2 Vaccine Protection against SARS-CoV-2 Infection in Qatar". The New England Journal of Medicine 385 (24): e83. December 2021. doi:10.1056/NEJMoa2114114. PMID 34614327. 
  25. ↑ "Effectiveness of the BNT162b2 Covid-19 Vaccine against the B.1.1.7 and B.1.351 Variants". The New England Journal of Medicine 385 (2): 187–189. July 2021. doi:10.1056/NEJMc2104974. PMID 33951357. 
  26. ↑ "(BRC)- (QU) CONDUCTS SIX RESEARCH PROJECTS ON COVID-19". http://www.qu.edu.qa/newsroom/BRC/(BRC)%E2%80%93-(QU)-conducts-six-researches-on-COVID%E2%80%9319. 
  27. ↑ 27.0 27.1 27.2 "Qatar University's Biomedical Research Center conducting research on COVID-19" (in en). The Peninsula Newspaper. 2020-03-29. https://thepeninsulaqatar.com/article/29/03/2020/Qatar-University%E2%80%99s-Biomedical-Research-Center-conducting-research-on-COVID-19. 
  28. ↑ 28.0 28.1 28.2 28.3 "Qatar- QU conducts research on coronavirus". MENAFN.COM. 2020-03-28. https://menafn.com/1099929849/Qatar-QU-conducts-research-on-coronavirus. 
  29. ↑ "Protection against the Omicron Variant from Previous SARS-CoV-2 Infection". The New England Journal of Medicine 386 (13): 1288–1290. March 2022. doi:10.1056/NEJMc2200133. PMID 35139269. 
  30. ↑ "Effect of mRNA Vaccine Boosters against SARS-CoV-2 Omicron Infection in Qatar". The New England Journal of Medicine 386 (19): 1804–1816. May 2022. doi:10.1056/NEJMoa2200797. PMID 35263534. 
  31. ↑ "Effects of Previous Infection and Vaccination on Symptomatic Omicron Infections". The New England Journal of Medicine 387 (1): 21–34. July 2022. doi:10.1056/NEJMoa2203965. PMID 35704396. 
  32. ↑ 32.0 32.1 32.2 32.3 "Qatar- QUBRC records rapid growth in published medical resea... | MENAFN.COM". 2020-11-27. https://menafn.com/1101197136/Qatar-QUBRC-records-rapid-growth-in-published-medical-research. 
  33. ↑ "Nanomedicine as a Potential Tool against Monkeypox". Vaccines 11 (2): 428. February 2023. doi:10.3390/vaccines11020428. PMID 36851305. 
  34. ↑ "Think like a Virus: Toward Improving Nanovaccine Development against SARS-CoV-2". Viruses 14 (7): 1553. July 2022. doi:10.3390/v14071553. PMID 35891532. 
  35. ↑ "Recent Developments in Nanomaterials-Based Drug Delivery and Upgrading Treatment of Cardiovascular Diseases". International Journal of Molecular Sciences 23 (3): 1404. January 2022. doi:10.3390/ijms23031404. PMID 35163328. 
  36. ↑ "Using Zebrafish for Investigating the Molecular Mechanisms of Drug-Induced Cardiotoxicity". BioMed Research International 2018: 1642684. 2018-09-27. doi:10.1155/2018/1642684. PMID 30363733. 
  37. ↑ "The First International Zebrafish Conference/Workshop in Qatar". Zebrafish 16 (5): 493–495. October 2019. doi:10.1089/zeb.2019.1786. PMID 31453757. 
  38. ↑ "Utilization Of Zebrafish As An Animal Model". Qatar University. August 2021. http://www.qu.edu.qa/research/brc/Training/basic-training-on-utilization-of-zebrafish-as-an-animal-model. 
  39. ↑ "Qatar International Zebrafish Workshop". Qatar University. April 2017. http://www.qu.edu.qa/conference/zebrafish-workshop. 
  40. ↑ "Qatar University workshop introduces 'zebrafish model' research" (in en). The Peninsula Newspaper. 2019-04-20. https://thepeninsulaqatar.com/article/20/04/2019/Qatar-University-workshop-introduces-%E2%80%98zebrafish-model%E2%80%99-research. 
  41. ↑ 41.0 41.1 "Facilities". Qatar University. 2023. http://www.qu.edu.qa/research/brc/facilities. 
  42. ↑ "QU Paves the Way in Research in Zebra Fish". 2019-04-14. http://www.qu.edu.qa/newsroom/Research/QU-paves-the-way-in-research-through-Zebrafish. 
  43. ↑ "The First International Zebrafish Conference/Workshop in Qatar | IZFS - International Zebrafish Society". 2019. https://www.izfs.org/newssplash/newssplash-issue-7-fall-2019/the-first-international-zebrafish-conferenceworkshop-in-qatar. 
  44. ↑ "Policy on Zebrafish Research, Ministry of Public Health, Department of Research Regulation". 2020. http://www.qu.edu.qa/static_file/qu/research/documents/qu_iacuc/Policy%20on%20Zebrafish%20Research.pdf. 
  45. ↑ "Certek, biosafety laboratory, custom built modular laboratories, modular laboratory, biosafety, BSL-3" (in en). https://certek-usa.com/clientele/clientele-list/. 
  46. ↑ "Profiling of Intestinal Microbiota in Patients Infected with Respiratory Influenza A and B Viruses". Pathogens 10 (6): 761. June 2021. doi:10.3390/pathogens10060761. PMID 34204203. 
  47. ↑ "Whole-Genome Sequencing for Molecular Characterization of Carbapenem-Resistant Enterobacteriaceae Causing Lower Urinary Tract Infection among Pediatric Patients". Antibiotics 10 (8): 972. August 2021. doi:10.3390/antibiotics10080972. PMID 34439022. 
  48. ↑ "Whole genome sequencing of marine organisms by Oxford Nanopore Technologies: Assessment and optimization of HMW-DNA extraction protocols". Ecology and Evolution 11 (24): 18505–18513. December 2021. doi:10.1002/ece3.8447. PMID 35003688. 

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