Organization:Rothberg Institute for Childhood Diseases
Template:Infobox nonprofit The Rothberg Institute For Childhood Diseases is a non-profit organization dedicated to finding a cure for rare childhood diseases such as Tuberous Sclerosis Complex (TSC). The organization was founded by Jonathan Rothberg and his wife in 2002 after their son was born with TSC.[1][2][3][4]
Located in Guilford, Connecticut, the organization was responsible for the CommunityTSC distributed computing project.
Dr. Rothberg graduated from Yale University in 1991.[3]
CommunityTSC
CommunityTSC Drug Design Optimization Lab (D2OL) was a distributed computing project developed by the Institute to test drug candidates interaction with a target molecule that is essential to the spread of the disease under scrutiny. By evaluating the energy level released by binding a small molecule drug candidate to the surface of a larger Target molecule (D2OL) determines the fitness of the particular candidate to a region of the Target structure known as the Active Site. This process is referred to as docking the drug candidate to the target. D2OL ended on April 15, 2009.
References
- ↑ "Yale Medicine Winter 2007: Alumni". Archived from the original on 2007-05-09. https://web.archive.org/web/20070509143429/http://yalemedicine.yale.edu/ym_wi07/faces.html. Retrieved 2016-11-14.
- ↑ Pollack, Andrew (2011-01-05). "Taking DNA Sequencing to the Masses" (in en-US). The New York Times. ISSN 0362-4331. https://www.nytimes.com/2011/01/05/health/05gene.html.
- ↑ 3.0 3.1 Belli, Brita (2018-03-20). "Alumnus Rothberg enlists students to solve next healthcare challenges" (in en). https://news.yale.edu/2018/03/20/alumnus-rothberg-enlists-students-solve-next-healthcare-challenges.
- ↑ Pollack, Andrew (2011-01-05). "Taking DNA Sequencing to the Masses" (in en-US). The New York Times. ISSN 0362-4331. https://www.nytimes.com/2011/01/05/health/05gene.html.
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