Orthogonal signal correction

From HandWiki
Orthogonal Signal Correction (OSC) is a spectral preprocessing technique that removes variation from a data matrix X that is orthogonal to the response matrix Y.[1] OSC was introduced by researchers at the University of Umea in 1998 and has since found  applications in domains including metabolomics.[2][3][4][5]

References

  1. Wold, Svante; Antti, Henrik; Lindgren, F; Ohman, J (1998), "Orthogonal signal correction of near-infrared spectra", Chemometrics and Intelligent Laboratory Systems 44: 175–185, doi:10.1016/s0169-7439(98)00109-9 
  2. "Systemic metabolic changes of traumatic critically ill patients revealed by an NMR-based metabonomic approach". J. Proteome Res. 8 (12): 5423–30. 2009. doi:10.1021/pr900576y. PMID 19835422. 
  3. "Evaluation of the proximal tubular function in individuals with primary renal hypouricemia: an NMR-based metabonomic study". NMR Biomed 22 (10): 1072–83. 2009. doi:10.1002/nbm.1415. PMID 19593759. 
  4. "1H NMR metabolomics study of age profiling in children". NMR Biomed 22 (8): 826–33. 2009. doi:10.1002/nbm.1395. PMID 19441074. 
  5. "Application of chemometrics to 1H NMR spectroscopic data to investigate a relationship between human serum metabolic profiles and hypertension". Analyst 128 (1): 32–6. 2003. doi:10.1039/b209155k. PMID 12572799.