Physics:V-EMF therapy

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Short description: Regenerative therapy based on electrostimulation

V-EMF therapy is a therapy that is based on the synergy between electromagnetic fields, vacuum and low-intensity electrostimulation. It is also known as Biodermogenesi. The electromagnetic field is generated with a variable frequency between 0.5 and 2 MHz.

Electromagnetic fields are able to promote the repair processes of skin lesions[1][2] with a reduction in healing time and scar size and with an increase in the re-epithelialization process.[3][4][5] They also promote the migration and subsequent stabilization of different cell types involved in the processes of regeneration, tissue engineering and wound care.[6]

The data in the literature show that the therapeutic application of electromagnetic fields allows to obtain satisfactory results in the regeneration of degenerated or traumatized or injured tissue[7][8][9] reaching the healing and regeneration of permanent lesions.[10][11][12] In addition, they have been shown to be useful in reducing fibrosis both in the treatment of cellulite[13] and in the treatment of fibrotic, hypertrophic and keloid scars.[14]

Similarly to electromagnetic fields, the application of vacuum, in this therapy adopted with negative pressure between 8 and 16 hundredths of Bar, has shown considerable effectiveness in reducing skin fibrosis due to cellulite and scarring.[15]

As for low-intensity electrostimulation, or electroporation, delivered at 5 VDC, it is able to increase skin nourishment.[16] The three forms of energy used simultaneously are the basis of V-EMF therapy, which has shown significant results in various fields of application. The therapeutic protocol has proven effective in the treatment of burn scars,[17][18] post-surgical trauma,[17][19] chemical burns,[20] stretch marks,[21][22][23][24] and in anti-aging therapy.[25]

See also

  • Biodermogenesi

References

  1. ↑ Pesce, Mirko; Patruno, Antonia; Speranza, Lorenza; Reale, Marcella (2013). "Extremely low frequency electromagnetic field and wound healing: implication of cytokines as biological mediators". European Cytokine Network 24 (1): 1–10. doi:10.1684/ecn.2013.0332. ISSN 1148-5493. PMID 23674517. https://www.jle.com/en/revues/ecn/revue.phtml. 
  2. ↑ Geng, D.Y.; Li, C.H.; Wan, X.W.; Xu, G.Z. (2014). "Biochemical kinetics of cell proliferation regulated by extremely low frequency electromagnetic field". Bio-Medical Materials and Engineering 24 (1): 1391–1397. doi:10.3233/BME-130943. PMID 24212036. https://journals.sagepub.com/doi/full/10.3233/BME-130943. 
  3. ↑ Ieran, M.; Zaffuto, S.; Bagnacani, M.; Annovi, M.; Moratti, A.; Cadossi, R. (1990). "Effect of low frequency pulsing electromagnetic fields on skin ulcers of venous origin in humans: A double-blind study" (in en). Journal of Orthopaedic Research 8 (2): 276–282. doi:10.1002/jor.1100080217. ISSN 0736-0266. PMID 2303961. https://onlinelibrary.wiley.com/doi/10.1002/jor.1100080217. 
  4. ↑ Ross, Christina; Harrison (2013). "Effect of pulsed electromagnetic field on inflammatory pathway markers in RAW 264.7 murine macrophages" (in en). Journal of Inflammation Research 6: 45–51. doi:10.2147/JIR.S40269. ISSN 1178-7031. PMID 23576877. 
  5. ↑ Cheing, Gladys Lai-Ying; Li, Xiaohui; Huang, Lin; Kwan, Rachel Lai-Chu; Cheung, Kwok-Kuen (2014). "Pulsed electromagnetic fields (PEMF) promote early wound healing and myofibroblast proliferation in diabetic rats" (in en). Bioelectromagnetics 35 (3): 161–169. doi:10.1002/bem.21832. ISSN 0197-8462. PMID 24395219. https://onlinelibrary.wiley.com/doi/10.1002/bem.21832. 
  6. ↑ Ross, Christina L. (2017). "The use of electric, magnetic, and electromagnetic field for directed cell migration and adhesion in regenerative medicine" (in en). Biotechnology Progress 33 (1): 5–16. doi:10.1002/btpr.2371. ISSN 8756-7938. PMID 27797153. https://aiche.onlinelibrary.wiley.com/doi/10.1002/btpr.2371. 
  7. ↑ Messerli, Mark A.; Graham, David M. (2011). "Extracellular Electrical Fields Direct Wound Healing and Regeneration". The Biological Bulletin 221 (1): 79–92. doi:10.1086/bblv221n1p79. ISSN 0006-3185. PMID 21876112. 
  8. ↑ Pilla, Arthur A. (2013-05-15). "Nonthermal electromagnetic fields: From first messenger to therapeutic applications". Electromagnetic Biology and Medicine 32 (2): 123–136. doi:10.3109/15368378.2013.776335. ISSN 1536-8378. PMID 23675615. 
  9. ↑ Boyette, Melissa Y.; Herrera-Soto, Jose A. (2012). "Treatment of Delayed and Nonunited Fractures and Osteotomies With Pulsed Electromagnetic Field in Children and Adolescents". Orthopedics 35 (7): e1051-5. doi:10.3928/01477447-20120621-20. ISSN 0147-7447. PMID 22784899. 
  10. ↑ Fredericks, Douglas C.; Nepola, James V.; Baker, Joy T.; Abbott, Joan; Simon, Bruce (2000). "Effects of Pulsed Electromagnetic Fields on Bone Healing in a Rabbit Tibial Osteotomy Model". Journal of Orthopaedic Trauma 14 (2): 93–100. doi:10.1097/00005131-200002000-00004. ISSN 0890-5339. PMID 10716379. 
  11. ↑ Bogie, Kath M.; Reger, Steven I.; Levine, Simon P.; Sahgal, Vinod (2000-06-30). "Electrical Stimulation for Pressure Sore Prevention and Wound Healing". Assistive Technology 12 (1): 50–66. doi:10.1080/10400435.2000.10132009. ISSN 1040-0435. PMID 11067577. 
  12. ↑ Martínez-Rodríguez, Alicia; Bello, Olalla; Fraiz, Manuel; Martinez-Bustelo, Sandra (2013-06-20). "The effect of alternating and biphasic currents on humans' wound healing: a literature review". International Journal of Dermatology 52 (9): 1053–1062. doi:10.1111/j.1365-4632.2012.05836.x. ISSN 0011-9059. PMID 23786603. 
  13. ↑ Valentim da Silva, Rodrigo Marcel; Barichello, Priscila Arend; Medeiros, Melyssa Lima; Mendonça, Waléria Cristina Miranda de; Dantas, Jung Siung Camel; Ronzio, Oscar Ariel; Froes, Patricia Meyer; Galadari, Hassan (2013). "Effect of Capacitive Radiofrequency on the Fibrosis of Patients with Cellulite". Dermatology Research and Practice 2013: 1–6. doi:10.1155/2013/715829. ISSN 1687-6105. PMID 24223586. 
  14. ↑ Hernández-Bule, María Luisa; Toledano-Macías, Elena; Pérez-González, Luis Alfonso; Martínez-Pascual, María Antonia; Fernández-Guarino, Montserrat (2023-07-01). "Anti-Fibrotic Effects of RF Electric Currents" (in en). International Journal of Molecular Sciences 24 (13). doi:10.3390/ijms241310986. ISSN 1422-0067. PMID 37446165. 
  15. ↑ Duscher, Dominik; Maan, Zeshaan N.; Wong, Victor W.; Rennert, Robert C.; Januszyk, Michael; Rodrigues, Melanie; Hu, Michael; Whitmore, Arnetha J. et al. (2014). "Mechanotransduction and fibrosis" (in en). Journal of Biomechanics 47 (9): 1997–2005. doi:10.1016/j.jbiomech.2014.03.031. PMID 24709567. 
  16. ↑ Pacini, Stefania; Punzi, Tiziana; Gulisano, Massimo; Cecchi, Fabiola; Vannucchi, Simonetta; Ruggiero, Marco (2006). "Transdermal Delivery of Heparin Using Pulsed Current Iontophoresis". Pharmaceutical Research 23 (1): 114–120. doi:10.1007/s11095-005-8923-z. ISSN 0724-8741. PMID 16362453. 
  17. ↑ 17.0 17.1 Nicoletti, Giovanni; Perugini, Paola; Bellino, Sara; Capra, Priscilla; Malovini, Alberto; Jaber, Omar; Tresoldi, Marco; Faga, Angela (2017). "Scar Remodeling with the Association of Monopolar Capacitive Radiofrequency, Electric Stimulation, and Negative Pressure". Photomedicine and Laser Surgery 35 (5): 246–258. doi:10.1089/pho.2016.4180. ISSN 1557-8550. PMID 28128685. 
  18. ↑ Veronese, Sheila; Aggarwal, Rajeev; Giovanelli, Tiziana; Sbarbati, Andrea (2024-02-11). "Hyper- and Hypopigmentation in a Subject with Fitzpatrick Skin Phototype VI: A New Treatment Option". Journal of Clinical Medicine 13 (4): 1036. doi:10.3390/jcm13041036. ISSN 2077-0383. PMID 38398349. 
  19. ↑ Veronese, Sheila; Beatini, Annalisa; Urbani, Claudio; Lanza, Eliana; Paz, Oscar Mosquera; Saussaye, Yannick; Lomuto, Michele; Sbarbati, Andrea (2022). "V-EMF treatment of facial scar: First results" (in en). Journal of Tissue Viability 31 (4): 614–618. doi:10.1016/j.jtv.2022.07.006. PMID 35853796. https://linkinghub.elsevier.com/retrieve/pii/S0965206X22000808. 
  20. ↑ Veronese, Sheila; Brunetti, Bruno; Minichino, Anna; Sbarbati, Andrea (2022-12-13). "Vacuum and Electromagnetic Fields Treatment to Regenerate a Diffuse Mature Facial Scar Caused by Sulfuric Acid Assault" (in en). Bioengineering 9 (12): 799. doi:10.3390/bioengineering9120799. ISSN 2306-5354. PMID 36551005. 
  21. ↑ Laura, Simona; Veronese, Sheila; Alberti, Giovanni; Bacci, Pier Antonio; Beatini, Annalisa; Fulgione, Elisabetta; Urbani, Claudio; Sbarbati, Andrea (2023-06-20). "Vacuum and electromagnetic field in synergy for skin rejuvenation: A retrospective study on 217 patients". Journal of Cosmetic Dermatology 22 (11): 2989–2995. doi:10.1111/jocd.15871. ISSN 1473-2130. PMID 37340588. 
  22. ↑ Bacci, P. A.; Alberti, G.; Amuso, D.; Artigiani, A.; Roig, V. Benitez; Nardo, V. Di; Garcia-Gimenez, V.; Greco, D. et al. (2021-06-01). "The synergy between vacuum and electromagnetic fields in the treatment of striae distensae: retrospective study on 917 patients with clinical and histological case records" (in en). Journal of Applied Cosmetology 39 (1): 2/13. ISSN 2974-6140. https://scientificeditorial.com/index.php/JAC/article/view/The-synergy-between-vacuum-and-electromagnetic-fieldsin-the-trea. 
  23. ↑ Scarano, Antonio; Sbarbati, Andrea; Amore, Roberto; L. Iorio, Eugenio; Ferraro, Giuseppe; Lorusso, Felice; Amuso, Domenico (2021). "A new treatment for stretch marks and skin ptosis with electromagnetic fields and negative pressure: A clinical and histological study". Journal of Cutaneous and Aesthetic Surgery 14 (2): 222–228. doi:10.4103/jcas.jcas_122_20. ISSN 0974-2077. PMID 34566367. 
  24. ↑ Veronese, Sheila; Bacci, Pier Antonio; Garcia-Gimenez, Victor (2024). "V-EMF therapy: A new painless and completely non-invasive treatment for striae gravidarum" (in en). Journal of Cosmetic Dermatology 23 (6): 2007–2014. doi:10.1111/jocd.16220. ISSN 1473-2130. PMID 38549181. 
  25. ↑ Laura, Simona; Veronese, Sheila; Alberti, Giovanni; Bacci, Pier Antonio; Beatini, Annalisa; Fulgione, Elisabetta; Urbani, Claudio; Sbarbati, Andrea (2023). "Vacuum and electromagnetic field in synergy for skin rejuvenation: A retrospective study on 217 patients" (in en). Journal of Cosmetic Dermatology 22 (11): 2989–2995. doi:10.1111/jocd.15871. ISSN 1473-2130. PMID 37340588. 



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