Rodrigues equation
From HandWiki
The Rodrigues equation is an equation used in chromatography to describe the efficiency of a bed of permeable (large-pore) particles. It is thus an extension of Van Deemter's equation. It was developed by Alirio E. Rodrigues et al..[1]
Equation
The equation is:
[math]\displaystyle{ HETP = A + \frac{B}{u} + C \cdot f( \lambda ) \cdot u }[/math]
Where
- HETP is the height equivalent to a theoretical plate
- A = Eddy diffusion
- B = Longitudinal diffusion
- C = Resistance to mass transfer
- u = Flow rate
- [math]\displaystyle{ f( \lambda ) = \frac{3}{ \lambda } \left [ \frac{1}{\tanh( \lambda )} - \frac{1}{ \lambda } \right ] }[/math]
- [math]\displaystyle{ \lambda }[/math] = Intraparticular Péclet number
References
- ↑ Alirio E. Rodrigues (10 October 1997). "Permeable packings and perfusion chromatography in protein separation". Journal of Chromatography B 699 (1–2): 47–61. doi:10.1016/S0378-4347(97)00197-7.
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