Single-shot multi-contrast X-ray imaging

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Single-shot multi-contrast x-ray imaging is an efficient and a robust x-ray imaging technique which is used to obtain three different and complementary types of information, i.e. absorption, scattering, and phase contrast from a single exposure of x-rays on a detector subsequently utilizing Fourier analysis/technique. Absorption is mainly due to the attenuation and Compton scattering from the object, while phase contrast corresponds to phase shift of x-rays.

The technique obtain images from the biological and non-biological objects. The research purposes include radiography, scattering imaging, differential phase contrast, and diffraction imaging. It is also possible to adjust and modify the experiment based on what information is of most importance. Almost every application that utilize this technique have the same approach, mathematics and science behind it such as the experimental setup, complementary information and Fourier analysis.

Single-shot multi-contrast x-ray imaging gained its importance recently in contrast to Talbot–Lau interferometer because of the less optical element such as diffraction gratings being used under it and hence obtaining every information digitally.

References

Spatial harmonic method [1] [2] [3] [4] [5] [6] [7] [8]

Interferometry-based setups [9] [10] [11] [12] [13]

Hybrid detectors and coded apertures

[14] [15] [16] [17] [18]



  1. ↑ Takeda, Mitsuo; Ina, Hideki; Kobayashi, Seiji (1982-01-01). "Fourier-transform method of fringe-pattern analysis for computer-based topography and interferometry". Journal of the Optical Society of America (The Optical Society) 72 (1): 156. doi:10.1364/josa.72.000156. ISSN 0030-3941. Bibcode: 1982JOSA...72..156T. http://staff.ustc.edu.cn/~jlxie/PD_refractive_index/%B8%C9%C9%E6%D2%C7-%BC%A4%B9%E2%B5%C8%C0%EB%D7%D3%CC%E5%B3%C9%CF%F1-josa-72-1-156%20%BC%A4%B9%E2%B5%C8%C0%EB%D7%D3%CC%E5%CC%F5%CE%C6%B4%A6%C0%EDFFT.pdf. 
  2. ↑ Bennett, Eric E.; Kopace, Rael; Stein, Ashley F.; Wen, Han (2010-10-29). "A grating-based single-shot x-ray phase contrast and diffraction method for in vivo imaging". Medical Physics (Wiley) 37 (11): 6047–6054. doi:10.1118/1.3501311. ISSN 0094-2405. PMID 21158316. Bibcode: 2010MedPh..37.6047B. 
  3. ↑ Wen, Han; Bennett, Eric E.; Hegedus, Monica M.; Rapacchi, Stanislas (2009). "Fourier X-ray Scattering Radiography Yields Bone Structural Information". Radiology (Radiological Society of North America (RSNA)) 251 (3): 910–918. doi:10.1148/radiol.2521081903. ISSN 0033-8419. PMID 19403849. 
  4. ↑ Wen, Harold H.; Bennett, Eric E.; Kopace, Rael; Stein, Ashley F.; Pai, Vinay (2010-06-03). "Single-shot x-ray differential phase-contrast and diffraction imaging using two-dimensional transmission gratings". Optics Letters (The Optical Society) 35 (12): 1932–1934. doi:10.1364/ol.35.001932. ISSN 0146-9592. PMID 20548343. Bibcode: 2010OptL...35.1932W. 
  5. ↑ Wen, H.; Bennett, E.E.; Hegedus, M.M.; Carroll, S.C. (2008). "Spatial Harmonic Imaging of X-ray Scattering—Initial Results". IEEE Transactions on Medical Imaging (Institute of Electrical and Electronics Engineers (IEEE)) 27 (8): 997–1002. doi:10.1109/tmi.2007.912393. ISSN 0278-0062. PMID 18672418. 
  6. ↑ Lynch, Susanna K.; Pai, Vinay; Auxier, Julie; Stein, Ashley F.; Bennett, Eric E.; Kemble, Camille K.; Xiao, Xianghui; Lee, Wah-Keat et al. (2011-07-22). "Interpretation of dark-field contrast and particle-size selectivity in grating interferometers". Applied Optics (The Optical Society) 50 (22): 4310–4319. doi:10.1364/ao.50.004310. ISSN 0003-6935. PMID 21833104. Bibcode: 2011ApOpt..50.4310L. 
  7. ↑ Stein, Ashley F.; Ilavsky, Jan; Kopace, Rael; Bennett, Eric E.; Wen, Han (2010-06-04). "Selective imaging of nano-particle contrast agents by a single-shot x-ray diffraction technique". Optics Express (The Optical Society) 18 (12): 13271–13278. doi:10.1364/oe.18.013271. ISSN 1094-4087. PMID 20588456. Bibcode: 2010OExpr..1813271S. 
  8. ↑ Liu, Yanan; Ahr, Brian; Linkin, Alexander; Diebold, Gerald J.; Rose-Petruck, Christoph (2011-06-07). "X-ray spatial harmonic imaging of phase objects". Optics Letters (The Optical Society) 36 (12): 2209–11. doi:10.1364/ol.36.002209. ISSN 0146-9592. PMID 21685969. Bibcode: 2011OptL...36.2209L. 
  9. ↑ Kottler, C.; David, C.; Pfeiffer, F.; Bunk, O. (2007). "A two-directional approach for grating based differential phase contrast imaging using hard x-rays". Optics Express (The Optical Society) 15 (3): 1175–1181. doi:10.1364/oe.15.001175. ISSN 1094-4087. PMID 19532346. Bibcode: 2007OExpr..15.1175K. 
  10. ↑ Sato, Genta; Itoh, Hidenosuke; Nagai, Kentaro; Nakamura, Takashi; Yamaguchi, Kimiaki; Kondoh, Takeshi; Handa, Soichiro; Ouchi, Chidane et al. (2012). "Single-shot X-ray phase-contrast imaging using two-dimensional gratings". 1466. AIP. p. 29. doi:10.1063/1.4742265. 
  11. ↑ Itoh, Hidenosuke; Nagai, Kentaro; Sato, Genta; Yamaguchi, Kimiaki; Nakamura, Takashi et al. (2011-02-04). "Two-dimensional grating-based X-ray phase-contrast imaging using Fourier transform phase retrieval". Optics Express (The Optical Society) 19 (4): 3339–46. doi:10.1364/oe.19.003339. ISSN 1094-4087. PMID 21369156. 
  12. ↑ Sato, Genta; Kondoh, Takeshi; Itoh, Hidenosuke; Handa, Soichiro; Yamaguchi, Kimiaki et al. (2011-09-08). "Two-dimensional gratings-based phase-contrast imaging using a conventional x-ray tube". Optics Letters (The Optical Society) 36 (18): 3551–3. doi:10.1364/ol.36.003551. ISSN 0146-9592. PMID 21931387. Bibcode: 2011OptL...36.3551S. 
  13. ↑ Nagai, Kentaro; Sato, Genta; Date, Takashi; Handa, Soichiro; Yamaguchi, Kimiaki et al. (2014-02-18). "A phase demodulation method with high spatial resolution for two-dimensional single-shot X-ray Talbot interferometry". Optics Express (The Optical Society) 22 (4): 4316–4328. doi:10.1364/oe.22.004316. ISSN 1094-4087. PMID 24663755. Bibcode: 2014OExpr..22.4316N. 
  14. ↑ Kagias, M.; Cartier, S.; Wang, Z.; Bergamaschi, A.; Dinapoli, R.; Mozzanica, A.; Schmitt, B.; Stampanoni, M. (2016-06-06). "Single shot x-ray phase contrast imaging using a direct conversion microstrip detector with single photon sensitivity". Applied Physics Letters (AIP Publishing) 108 (23): 234102. doi:10.1063/1.4948584. ISSN 0003-6951. Bibcode: 2016ApPhL.108w4102K. https://www.dora.lib4ri.ch/psi/islandora/object/psi%3A8042. 
  15. ↑ Das, Mini; Liang, Zhihua (2014-10-31). "Spectral x-ray phase contrast imaging for single-shot retrieval of absorption, phase, and differential-phase imagery". Optics Letters (The Optical Society) 39 (21): 6343–6. doi:10.1364/ol.39.006343. ISSN 0146-9592. PMID 25361350. Bibcode: 2014OptL...39.6343D. 
  16. ↑ Krejci, F; Jakubek, J; Kroupa, M (2011-01-11). "Single grating method for low dose 1-D and 2-D phase contrast X-ray imaging". Journal of Instrumentation (IOP Publishing) 6 (1): C01073. doi:10.1088/1748-0221/6/01/c01073. ISSN 1748-0221. Bibcode: 2011JInst...6.1073K. 
  17. ↑ Krejci, Frantisek; Jakubek, Jan; Kroupa, Martin (2010). "Hard x-ray phase contrast imaging using single absorption grating and hybrid semiconductor pixel detector". Review of Scientific Instruments (AIP Publishing) 81 (11): 113702–113702–5. doi:10.1063/1.3499372. ISSN 0034-6748. PMID 21133473. Bibcode: 2010RScI...81k3702K. 
  18. ↑ Morgan, Kaye S.; Paganin, David M.; Siu, Karen K. W. (2011-09-23). "Quantitative single-exposure x-ray phase contrast imaging using a single attenuation grid". Optics Express (The Optical Society) 19 (20): 19781–9. doi:10.1364/oe.19.019781. ISSN 1094-4087. PMID 21996920. Bibcode: 2011OExpr..1919781M. 
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