Software:Computational Anatomy Toolbox
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| Developer(s) | Structural Brain Mapping Group Christian Gaser Robert Dahnke |
|---|---|
| Stable release | 12.9
/ 25 May 2024 |
| Repository | github |
| Written in | Matlab, C |
| Operating system | Linux, macOS, Windows |
| Platform | MATLAB, SPM |
| Type | Neuroimaging data analysis |
| License | GNU General Public License |
| Website | neuro-jena |
CAT (Computational Anatomy Toolbox) is a free and open source software package used for the analysis of structural brain imaging data, in particular magnetic resonance imaging (MRI) [1]. Developed by Christian Gaser and Robert Dahnke of the Structural Brain Mapping Group at the University of Jena, CAT is an extension of the SPM software platform. It is widely recognised in the neuroscience and neuroimaging communities as a robust and versatile tool for studying brain morphology.
Features
- Voxel-Based Morphometry (VBM): Provides tools for analysing brain tissue volume, focusing on gray matter, white matter, and cerebrospinal fluid.
- Surface-Based Morphometry (SBM): Offers capabilities for cortical surface analysis, including measurements of cortical thickness [2], folding [3], and gyrification [4].
- Region- or Label-Based Morphometry: Allows for structural assessments within predefined brain regions or anatomical labels.
- Integrated Quality Control: Automated pipelines ensure high-quality data preprocessing and analysis.
- Longitudinal Analysis: Supports the study of brain changes over time through longitudinal data analysis [5].
Applications
CAT is widely used to study brain structure in various populations, including studies of neurodevelopment, ageing, neurodegenerative diseases, and mental disorders [6]. Its integration with SPM makes it a versatile tool for both basic research and clinical studies.
Integration with SPM
CAT is designed to work within the SPM environment, taking advantage of SPM's statistical analysis, image preprocessing, and data visualisation capabilities. This integration allows users to combine the structural analysis capabilities of CAT with the functional and statistical tools provided by SPM.
Related software
References
- ↑ "CAT: a computational anatomy toolbox for the analysis of structural MRI data". GigaScience 13: giae049. Aug 2024. doi:10.1093/gigascience/giae049. PMID 39102518.
- ↑ "Cortical thickness and central surface estimation". NeuroImage 65: 336–48. Jan 2013. doi:10.1016/j.neuroimage.2012.09.050. PMID 23041529.
- ↑ "Local cortical surface complexity maps from spherical harmonic reconstructions". NeuroImage 56 (3): 961–73. Jun 2011. doi:10.1016/j.neuroimage.2011.02.007. PMID 21315159.
- ↑ "A curvature-based approach to estimate local gyrification on the cortical surface". NeuroImage 29 (4): 1224–30. Jul 2009. doi:10.1016/j.neuroimage.2005.08.049. PMID 16223589.
- ↑ "Neuroplasticity: changes in grey matter induced by training". Nature 427 (6972): 311–2. Jan 2004. doi:10.1038/427311a. PMID 14737157.
- ↑ "Use of neuroanatomical pattern classification to identify subjects in at-risk mental states of psychosis and predict disease transition". Arch Gen Psychiatry 66 (7): 700–12. Jul 2009. doi:10.1001/archgenpsychiatry.2009.62. PMID 19581561.
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