Unsolved:Green coffee extract

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Green coffee extract
Alternative medicine
File:McCaskill Takes Aim at Diet Scams That Are 'A Crisis in Consumer Protection'.webm
McCaskill speaks about diet scams including green coffee extract

Green coffee extract is an extract of unroasted, green coffee beans. It is used in the Swiss water process for decaffeinating coffee. It has also been used as a weight-loss supplement and as an ingredient in other weight-loss products, although there is insufficient clinical evidence that it is effective or safe for such uses.[1] In 2014, one of the primary trials showing benefit was retracted and the company that sponsored the study, Applied Food Sciences, was fined by the Federal Trade Commission for making baseless weight-loss claims using the flawed study.[2] Green coffee extract can also be prepared as an infusion from green coffee beans.[3]

Research

A 2011 review found tentative evidence that green coffee extract promotes weight loss; however, the quality of the evidence was poor.[1][4][5] A larger 2017 review assessed the effects of chlorogenic acid, the main phenolic compound in green coffee extract, determining that human studies to date were of poor quality and that no conclusions could be drawn from them.[6]

History

In April and September 2012, The Dr. Oz Show featured green coffee extract, and conducted its own non-scientific study as to its efficacy. The guest on that show, Lindsey Duncan, had been fined $9 million by the Federal Trade Commission for making deceptive and unsubstantiated claims related to green coffee products promoted on The Dr. Oz Show.[7][8]

Controversy

Fortune magazine reported in June 2014 that the benefits of consuming green coffee bean extract had been largely disproved by studies to date, and that green coffee extract has been the subject of Federal Trade Commission action against a Florida company and the subject of Senate hearings against misleading advertising for weight loss products.[9]

In May 2014, the Federal Trade Commission (FTC) charged the Florida-based manufacturers of a product called Pure Green Coffee with deceiving consumers with false weight loss claims.[10] The FTC said that reliance on the Vinson study was deceptive since serious methodological flaws render its results unreliable.[11][12]

On June 17, 2014, the U.S. Senate subcommittee on Science, and Transportation Committee held hearings to discuss weight-loss products and consumer protection.[13] During the hearings, green coffee extract was cited often as an example of a "phony" product sold to consumers.[9] When Dr. Oz. defended his endorsement of green coffee extract and other weight loss products on his show, Senator Claire McCaskill stated that the "scientific community is almost monolithic against you in terms of the efficacy of the three products that you call miracles."[13] During the hearing, Dr. Oz stated "I actually do personally believe in the items I talk about on the show. I passionately study them. I recognize they don’t have the scientific muster to present as fact but nevertheless I would give my audience the advice I give my family all the time, and I have given my family these products. Specifically the ones you mentioned, then I’m comfortable with that part." He said he believes in them "as short-term crutches, and even has his family try them. But there's no long-term miracle pill out there without diet and exercise."[14]

References

  1. 1.0 1.1 Onakpoya, I; Terry, R; Ernst, E (2011). "The use of green coffee extract as a weight loss supplement: a systematic review and meta-analysis of randomised clinical trials.". Gastroenterology Research and Practice 2011: 1–6. doi:10.1155/2011/382852. PMID 20871849. 
  2. "Green Coffee Bean Manufacturer Settles FTC Charges of Pushing its Product Based on Results of "Seriously Flawed" Weight-Loss Study: Applied Food Sciences Inc. Will Pay $3.5 Million and Must Substantiate Future Claims". Federal Trade Commission. September 8, 2014. http://www.ftc.gov/news-events/press-releases/2014/09/green-coffee-bean-manufacturer-settles-ftc-charges-pushing-its. 
  3. Macheiner, Lukas; Schmidt, Anatol; Schreiner, Matthias; Mayer, Helmut K. (2019). "Green coffee infusion as a source of caffeine and chlorogenic acid". Journal of Food Composition and Analysis 84: 103307. doi:10.1016/j.jfca.2019.103307. 
  4. Hill, Tim (2014). "Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects [Retraction"]. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 7: 467. doi:10.2147/DMSO.S75357. PMID 25340633. 
  5. "Authors retract green coffee bean diet paper touted by Dr. Oz". Oct 20, 2014. http://retractionwatch.com/2014/10/20/authors-retract-green-coffee-bean-diet-paper-touted-by-dr-oz/. Retrieved 22 October 2014. 
  6. Tajik, N; Tajik, M; Mack, I; Enck, P (8 April 2017). "The potential effects of chlorogenic acid, the main phenolic components in coffee, on health: a comprehensive review of the literature.". European Journal of Nutrition 56 (7): 2215–2244. doi:10.1007/s00394-017-1379-1. PMID 28391515. 
  7. "Government confirms one of Dr. Oz's favored diet pills is a total hoax". January 26, 2015. https://www.vox.com/2015/1/26/7916745/green-coffee-bean. 
  8. "Marketer Who Promoted a Green Coffee Bean Weight-Loss Supplement Agrees to Settle FTC Charges: Used Appearances on Dr. Oz, Other Shows to Launch Ad Campaign". Federal Trade Commission. January 26, 2015. http://www.ftc.gov/news-events/press-releases/2015/01/marketer-who-promoted-green-coffee-bean-weight-loss-supplement. 
  9. 9.0 9.1 Benjamin Snyder (June 18, 2014). "Can coffee beans blemish the Dr. Oz brand?". Fortune magazine. http://fortune.com/2014/06/18/dr-oz-coffee-beans-senate/. 
  10. "FTC Charges Green Coffee Bean Sellers with Deceiving Consumers through Fake News Sites and Bogus Weight Loss Claims". U.S. Federal Trade Commission. May 19, 2014. http://www.ftc.gov/news-events/press-releases/2014/05/ftc-charges-green-coffee-bean-sellers-deceiving-consumers-through. Retrieved March 4, 2015. 
  11. "Complaint For Permanent Injunction And Other Equitable Relief". Federal Trade Commission. May 15, 2014. http://www.ftc.gov/system/files/documents/cases/140519npbcmpt_0.pdf. 
  12. Scott Gavura (July 5, 2012). "Dr. Oz and Green Coffee Beans – More Weight Loss Pseudoscience". Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy (Science-Based Medicine) 5 (5): 21–27. doi:10.2147/DMSO.S27665. PMID 22291473. PMC 3267522. http://www.sciencebasedmedicine.org/dr-oz-and-green-coffee-beans-more-weight-loss-pseudoscience/. 
  13. 13.0 13.1 Shushannah Wasshe (June 17, 2014). "Dr. Oz Scolded by Senators for 'Miracle' Weight Loss Claims". ABC News. https://abcnews.go.com/blogs/politics/2014/06/dr-oz-scolded-by-senators-for-miracle-weight-loss-claims/. Retrieved March 4, 2015. 
  14. Reilly, Mollie (June 17, 2014). "Dr. Oz Grilled In Congress, Admits Weight Loss Products He Touts Don't Pass 'Scientific Muster'". Huffington Post. http://www.huffingtonpost.com/2014/06/17/dr-oz-congress_n_5504209.html. Retrieved March 4, 2015.