Template:Relative affinities of nandrolone and related steroids
From HandWiki
Revision as of 14:39, 11 July 2021 by imported>Jworkorg (import)
| Compound | PR | AR | ER | GR | MR | SHBG | CBG |
|---|---|---|---|---|---|---|---|
| Nandrolone | 20 | 154–155 | <0.1 | 0.5 | 1.6 | 1–16 | 0.1 |
| Testosterone | 1.0–1.2 | 100 | <0.1 | 0.17 | 0.9 | 19–82 | 3–8 |
| Estradiol | 2.6 | 7.9 | 100 | 0.6 | 0.13 | 8.7–12 | <0.1 |
| Notes: Values are percentages (%). Reference ligands (100%) were progesterone for the PR, testosterone for the AR, estradiol for the ER, dexamethasone for the GR, aldosterone]] for the MR, dihydrotestosterone for SHBG, and cortisol for CBG. Sources: [1][2][3][4][5][6][7][8] | |||||||
Template documentationReferences
- ↑ "Steroid flexibility and receptor specificity". J. Steroid Biochem. 13 (1): 45–59. January 1980. doi:10.1016/0022-4731(80)90112-0. PMID 7382482.
- ↑ "Towards the mapping of the progesterone and androgen receptors". J. Steroid Biochem. 27 (1–3): 255–69. 1987. doi:10.1016/0022-4731(87)90317-7. PMID 3695484.
- ↑ "Steroid hormone receptors and pharmacology". J. Steroid Biochem. 12: 143–57. January 1980. doi:10.1016/0022-4731(80)90264-2. PMID 7421203.
- ↑ "Unique steroid congeners for receptor studies". Cancer Res. 38 (11 Pt 2): 4186–98. November 1978. PMID 359134. http://cancerres.aacrjournals.org/content/38/11_Part_2/4186.short.
- ↑ "Affiliations among steroid receptors as revealed by multivariate analysis of steroid binding data". J. Steroid Biochem. Mol. Biol. 48 (1): 31–46. January 1994. doi:10.1016/0960-0760(94)90248-8. PMID 8136304.
- ↑ "Relative binding affinity of anabolic-androgenic steroids: comparison of the binding to the androgen receptors in skeletal muscle and in prostate, as well as to sex hormone-binding globulin". Endocrinology 114 (6): 2100–6. June 1984. doi:10.1210/endo-114-6-2100. PMID 6539197.
- ↑ "Steroid structural requirements for high affinity binding to human sex steroid binding protein (SBP)". Steroids 38 (3): 243–62. September 1981. doi:10.1016/0039-128X(81)90061-1. PMID 7197818.
- ↑ "Transport of steroid hormones: interaction of 70 drugs with testosterone-binding globulin and corticosteroid-binding globulin in human plasma". J. Clin. Endocrinol. Metab. 53 (1): 69–75. July 1981. doi:10.1210/jcem-53-1-69. PMID 7195405.
