Biology:Saccharopolyspora erythraea
From HandWiki
Short description: Species of bacterium
| Saccharopolyspora erythraea | |
|---|---|
| |
Scientific classification 
| |
| Domain: | Bacteria |
| Phylum: | Actinomycetota |
| Class: | Actinomycetia |
| Order: | Pseudonocardiales |
| Family: | Pseudonocardiaceae |
| Genus: | Saccharopolyspora |
| Species: | S. erythraea
|
| Binomial name | |
| Saccharopolyspora erythraea (Waksman 1923) Labeda 1987
| |
| Synonyms[1] | |
| |
Saccharopolyspora erythraea is a species of actinomycete bacteria within the genus Saccharopolyspora.
Saccharopolyspora erythraea produces the macrolide antibiotic erythromycin.[2] Cytochrome P450 eryF (CYP107A1) originally from the bacterium is responsible for the biosynthesis of the antibiotic by C6-hydroxylation of the macrolide 6-deoxyerythronolide B.[3][4]
Small non-coding RNAs have been suggested to be involved in regulation of the secondary metabolite biosynthesis.[5]
References
- ↑ Labeda, David P. (1987-01-01). "Transfer of the Type Strain of Streptomyces erythraeus (Waksman 1923) Waksman and Henrici 1948 to the Genus Saccharopolyspora Lacey and Goodfellow 1975 as Saccharopolyspora erythraea sp. nov., and Designation of a Neotype Strain for Streptomyces erythraeus". International Journal of Systematic Bacteriology 37 (1): 19. doi:10.1099/00207713-37-1-19.
- ↑ Oliynyk, Markiyan; Samborskyy, Markiyan; Lester, John B.; Mironenko, Tatiana; Scott, Nataliya; Dickens, Shilo; Haydock, Stephen F.; Leadlay, Peter F. (2007). "Complete genome sequence of the erythromycin-producing bacterium : Saccharopolyspora erythraea: NRRL23338". Nature Biotechnology 25 (4): 447–453. doi:10.1038/nbt1297. PMID 17369815.
- ↑ Cupp-Vickery, JR; Poulos, TL (February 1995). "Structure of cytochrome P450eryF involved in erythromycin biosynthesis.". Nature Structural Biology 2 (2): 144–53. doi:10.1038/nsb0295-144. PMID 7749919.
- ↑ Harris, DL (20 September 2002). "Oxidation and electronic state dependence of proton transfer in the enzymatic cycle of cytochrome P450 eryF". Journal of Inorganic Biochemistry 91 (4): 568–85. doi:10.1016/s0162-0134(02)00477-4. PMID 12237223.
- ↑ Liu, Wei-Bing; Shi, Yang; Yao, Li-Li; Zhou, Ying; Ye, Bang-Ce (2013-01-01). "Prediction and characterization of small non-coding RNAs related to secondary metabolites in Saccharopolyspora erythraea". PLOS ONE 8 (11): e80676. doi:10.1371/journal.pone.0080676. ISSN 1932-6203. PMID 24236194. Bibcode: 2013PLoSO...880676L.
External links
Wikidata ☰ Q7396613 entry
 |  |
