Chemistry:Amoscanate

Amoscanate

Names
Preferred IUPAC name 4-Isothiocyanato-N-(4-nitrophenyl)aniline
Other names 4-Isothiocyanato-4′-nitrodiphenylamine Nithiocyamine
Identifiers
CAS Number	26328-53-0 Y
3D model (JSmol)	Interactive image Interactive image
ChEBI	CHEBI:38944 Y
ChEMBL	ChEMBL93385 Y
ChemSpider	30904 Y
PubChem CID	33488
UNII	X0MK46CVRB Y
InChI InChI=1S/C13H9N3O2S/c17-16(18)13-7-5-12(6-8-13)15-11-3-1-10(2-4-11)14-9-19/h1-8,15H Y Key: DKVNAGXPRSYHLB-UHFFFAOYSA-N Y InChI=1/C13H9N3O2S/c17-16(18)13-7-5-12(6-8-13)15-11-3-1-10(2-4-11)14-9-19/h1-8,15H
SMILES O=N(=O)c1ccc(Nc2ccc(cc2)N=C=S)cc1 [O-] [N+](=O)c1ccc(cc1)Nc2ccc(N=C=S)cc2
Properties
Chemical formula	C13H9N3O2S
Molar mass	271.29 g·mol−1
Melting point	204 to 206 °C (399 to 403 °F; 477 to 479 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

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Amoscanate (INN), also known as nithiocyamine, is an experimental anthelmintic agent of the aryl isothiocyanate class which was found to be highly effective in animals against the four major species of schistosomes which infect humans, and is also highly active against hookworm infection. However, significant liver toxicity was seen in lab animals at higher doses. The ether analogue of amoscanate, nitroscanate, is used in veterinary medicine as an anthelmintic.

Amoscanate was developed by Ciba.