Chemistry:Kidamycin
From HandWiki
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| Other names
Rubiflavin B
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3D model (JSmol)
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PubChem CID
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| Properties | |
| C39H48N2O9 | |
| Molar mass | 688.818 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Kidamycin is an anthracycline antibiotic with anticancer activity.[1] It was first synthesized from a strain of streptomyces bacteria isolated from a soil sample.[2] In clinical trials, Kindamycin showed high effect against gram positive bacteria as well as multiple cancer models including Ehrlich ascites carcinoma, Sarcoma 180, NF-sarcoma, and Yoshida sarcoma.[3]
References
- ↑ Furukawa, M.; Hayakawa, I.; Ohta, G.; Iitaka, Y. (1 January 1971). "Structure and chemistry of kidamycin" (in en). Tetrahedron 31 (23): 2989–2995. doi:10.1016/0040-4020(75)80324-3. https://linkinghub.elsevier.com/retrieve/pii/0040402075803243.
- ↑ Kanda, N. (Sep 1971). "A new antitumor antibiotic, kidamycin. I. Isolation, purification and properties of kidamycin.". The Journal of Antibiotics 24 (9): 599–606. doi:10.7164/antibiotics.24.599. PMID 5132247.
- ↑ Kanda, Nobuo; Kono, Morihiro; Asano, Kazuo (1972). "A New Antitumor Antibiotic, Kidamycin" (in en). The Journal of Antibiotics 25 (10): 553–556. doi:10.7164/antibiotics.25.553. ISSN 0021-8820. PMID 4648309. https://www.jstage.jst.go.jp/article/antibiotics1968/25/10/25_10_553/_article.
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