Biology:MED30

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example
Med30
Identifiers
SymbolMed30
PfamPF11315
InterProIPR021019

Mediator of RNA polymerase II transcription subunit 30 is an enzyme that in humans is encoded by the MED30 gene.[1] It represents subunit Med30 of the Mediator complex and is metazoan-specific,[2] having no homologues in yeasts.

Interactions

MED30 has been shown to interact with MED22.[3]

References

  1. "Entrez Gene: THRAP6 thyroid hormone receptor associated protein 6". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=90390. 
  2. "Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s". Molecular and Cellular Biology 22 (8): 2842–52. April 2002. doi:10.1128/MCB.22.8.2842-2852.2002. PMID 11909976. 
  3. "Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3". The Journal of Biological Chemistry 278 (17): 15123–7. April 2003. doi:10.1074/jbc.C300054200. PMID 12584197. 

Further reading


This article incorporates text from the public domain Pfam and InterPro: IPR021019