Biology:RNF20
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
E3 ubiquitin-protein ligase BRE1A is an enzyme that in humans is encoded by the RNF20 gene.[1][2][3][4][5]
The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. Yeast BRE1 is a ubiquitin ligase required for the ubiquitination of histone H2B and the methylation of histone H3.[5]
See also
References
- ↑ "The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions". Mol Cell 20 (5): 759–70. Dec 2005. doi:10.1016/j.molcel.2005.11.012. PMID 16337599.
- ↑ "The Paf1 complex is essential for histone monoubiquitination by the Rad6-Bre1 complex, which signals for histone methylation by COMPASS and Dot1p". J Biol Chem 278 (37): 34739–42. Sep 2003. doi:10.1074/jbc.C300269200. PMID 12876294.
- ↑ "The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression". Genes Dev 22 (19): 2664–76. Oct 2008. doi:10.1101/gad.1703008. PMID 18832071.
- ↑ "Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor". Mol Biol Cell 20 (3): 757–68. Feb 2009. doi:10.1091/mbc.E08-09-0983. PMID 19037095.
- ↑ 5.0 5.1 "Entrez Gene: RNF20 ring finger protein 20". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56254.
Further reading
- "Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas.". Proc. Natl. Acad. Sci. U.S.A. 97 (18): 10209–13. 2000. doi:10.1073/pnas.180316097. PMID 10954754. Bibcode: 2000PNAS...9710209L.
- "Coronary arteries from human cardiac allografts with chronic rejection contain oligoclonal T cells: persistence of identical clonally expanded TCR transcripts from the early post-transplantation period (endomyocardial biopsies) to chronic rejection (coronary arteries).". J. Immunol. 165 (6): 3469–83. 2000. doi:10.4049/jimmunol.165.6.3469. PMID 10975868.
- "The V lambda J lambda repertoire in human fetal spleen: evidence for positive selection and extensive receptor editing.". J. Immunol. 165 (11): 6322–33. 2001. doi:10.4049/jimmunol.165.11.6322. PMID 11086069.
- "Oligoclonal IgA response in the vascular wall in acute Kawasaki disease.". J. Immunol. 166 (2): 1334–43. 2001. doi:10.4049/jimmunol.166.2.1334. PMID 11145718.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "A conserved RING finger protein required for histone H2B monoubiquitination and cell size control.". Mol. Cell 11 (1): 261–6. 2003. doi:10.1016/S1097-2765(02)00826-2. PMID 12535538.
- "Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter.". Mol. Cell 11 (1): 267–74. 2003. doi:10.1016/S1097-2765(02)00802-X. PMID 12535539.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369–74. 2004. doi:10.1038/nature02465. PMID 15164053. Bibcode: 2004Natur.429..369H.
- "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. 2004. doi:10.1073/pnas.0404720101. PMID 15302935. Bibcode: 2004PNAS..10112130B.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Nucleolar proteome dynamics.". Nature 433 (7021): 77–83. 2005. doi:10.1038/nature03207. PMID 15635413. Bibcode: 2005Natur.433...77A.
- "Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation.". Mol. Cell 20 (4): 601–11. 2006. doi:10.1016/j.molcel.2005.09.025. PMID 16307923.
External links
- RNF20+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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