Biology:USP36

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Ubiquitin-specific protease 36 is an enzyme that in humans is encoded by the USP36 gene. [1] [2]

This gene encodes a member of the ubiquitin-specific protease family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the nucleoli and deubiquitinate nucleophosmin and fibrillarin[3]

References

  1. "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet 4 (7): 544–558. Jul 2003. doi:10.1038/nrg1111. PMID 12838346. 
  2. "Entrez Gene: USP36 ubiquitin specific peptidase 36". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57602. 
  3. "Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36.". J Cell Sci 122 (Pt 5): 678–86. Mar 2009. doi:10.1242/jcs.044461. PMID 19208757. 

Further reading