Biology:Mir-320

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Short description: RNA molecule
mir-320
RF00736.png
Conserved secondary structure of mir-320
Identifiers
Symbolmir-320
RfamRF00736
miRBase familyMIPF0000163
Other data
RNA typemicroRNA
Domain(s)Eukaryota;
PDB structuresPDBe

In molecular biology mir-320 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.

The biogenesis of miR-320 is different from the canonical Microprocessor-dependent miRNAs. The pre-miR-320 is transcribed directly as a precursor microRNA hairpin and thus contains a 5′ m7G-cap.

See also

References

  1. "Temporal and spatial regulation of miR-320 in the uterus during embryo implantation in the rat.". Int J Mol Sci 11 (2): 719–730. 2010. doi:10.3390/ijms11020719. PMID 20386663. 
  2. "MiR-320 and miR-494 affect cell cycles of primary murine bronchial epithelial cells exposed to benzo[a]pyrene". Toxicol in Vitro 24 (3): 928–935. 2010. doi:10.1016/j.tiv.2009.11.013. PMID 19925859. 
  3. "Changes in microRNA profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes". Clin Exp Pharmacol Physiol 36 (9): e32–e39. 2009. doi:10.1111/j.1440-1681.2009.05207.x. PMID 19473196. 
  4. "MicroRNA-320 is involved in the regulation of cardiac ischemia/reperfusion injury by targeting heat-shock protein 20". Circulation 119 (17): 2357–2366. 2009. doi:10.1161/CIRCULATIONAHA.108.814145. PMID 19380620. 
  5. "miR-320 targets transferrin receptor 1 (CD71) and inhibits cell proliferation". Exp Hematol 37 (2): 245–255. 2009. doi:10.1016/j.exphem.2008.10.002. PMID 19135902. 
  6. "MicroRNA-320 expression in myocardial microvascular endothelial cells and its relationship with insulin-like growth factor-1 in type 2 diabetic rats". Clin Exp Pharmacol Physiol 36 (2): 181–188. 2009. doi:10.1111/j.1440-1681.2008.05057.x. PMID 18986336. 
  7. Ling, HY; Ou, HS; Feng, SD; Zhang, XY; Tuo, QH; Chen, LX; Zhu, BY; Gao, ZP et al. (September 2009). "CHANGES IN microRNA (miR) profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes.". Clinical and Experimental Pharmacology & Physiology 36 (9): e32–9. doi:10.1111/j.1440-1681.2009.05207.x. PMID 19473196. 
  8. Xie, M; Li, M; Vilborg, A; Lee, N; Yartseva, V; Sestan, N; Steitz, J (September 2013). "Mammalian 5′-Capped MicroRNA Precursors that Generate a Single MicroRNA.". Cell 155 (7): 1568–1580. doi:10.1016/j.cell.2013.11.027. PMID 24360278. 

External links