Medicine:Dextran 70
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| Trade names | RescueFlow, others |
| AHFS/Drugs.com | Monograph |
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| Routes of administration | intravenous |
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| Molar mass | 70000 Da |
Dextran 70 is a type of fluid given by injection into a vein to expand blood volume.[1] Specifically it is used for shock such as that caused by bleeding or burns when blood transfusions are not quickly available.[2] However, it does not carry oxygen.[2]
Common side effects include vomiting, fever, and joint pains.[2] Other side effects include allergic reactions and poor blood clotting.[1] It is not recommended in people with kidney failure, significant heart failure, or a clotting disorder.[2] It is not recommended during pregnancy.[3] It works by pulling fluid from the extravascular space into the blood vessels.[2]
Dextran 70 was approved for medical use in 1947.[4] It is on the World Health Organization's List of Essential Medicines.[5] It comes in either sodium chloride solution or glucose solution.[2]
References
- ↑ 1.0 1.1 WHO Model Formulary 2008. World Health Organization. 2009. pp. 248,257–58,279,287. ISBN 9789241547659.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 "Dextran 70". The American Society of Health-System Pharmacists. https://www.drugs.com/monograph/dextran-70.html.
- ↑ British national formulary : BNF 69 (69 ed.). British Medical Association. 2015. p. 686. ISBN 9780857111562.
- ↑ (in en) Industrial Gums: Polysaccharides and Their Derivatives (3 ed.). Academic Press. 2012. p. 411. ISBN 9780080926544. https://books.google.com/books?id=UziD3opt5-wC&pg=PA411.
- ↑ World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. 2019. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
External links
- "Dextran 70". Drug Information Portal. U.S. National Library of Medicine. https://druginfo.nlm.nih.gov/drugportal/name/dextran%2070.
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