Chemistry:1-Methylcytosine

Short description: Chemical compound

1-Methylcytosine

Names
Preferred IUPAC name 4-Amino-1-methylpyrimidin-2(1H)-one
Identifiers
CAS Number	1122-47-0 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:39624 Y
ChEMBL	ChEMBL500883
ChemSpider	71474 Y
MeSH	1-Methylcytosine
PubChem CID	79143
UNII	1J54NE82RV Y
InChI InChI=1S/C5H7N3O/c1-8-3-2-4(6)7-5(8)9/h2-3H,1H3,(H2,6,7,9) Y Key: HWPZZUQOWRWFDB-UHFFFAOYSA-N Y InChI=1S/C5H7N3O/c1-8-3-2-4(6)7-5(8)9/h2-3H,1H3,(H2,6,7,9) Key: HWPZZUQOWRWFDB-UHFFFAOYSA-N
SMILES CN1C=CC(=NC1=O)N
Properties
Chemical formula	C5H7N3O
Molar mass	125.131 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

1-Methylcytosine is a methylated form of the DNA base cytosine.

In 1-methylcytosine, a methyl group is attached to the 1st atom in the 6-atom ring. This methyl group distinguishes 1-methylcytosine from cytosine.

History

Miriam Rossi worked on the refinement of 1-methylcytosine.

1-Methylcytosine is used as a nucleobase of hachimoji DNA, in which it pairs with isoguanine.